8 days in South Carolina Itinerary
Created using Inspirock South Carolina itinerary planner
Start: Seattle
Fly
1
Greenville
Drive
2
Myrtle Beach
— 2 nights
Drive
3
Charleston
— 4 nights
Drive
4
Hilton Head
— 1 night
Fly
End: Seattle
Wed, Sep 27 - Wed, Oct 4
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View full calendar
Textile Center of the World
The largest city in "upstate" South Carolina, Greenville has grown around the natural wonders of waterfalls located in the downtown area.Start off your visit on the 27th (Wed): take in the views from Liberty Bridge and then admire the sheer force of Falls Park on the Reedy.
To see reviews, maps, photos, and more tourist information, read Greenville online itinerary planner.
Seattle to Greenville is an approximately 8-hour flight. You can also drive; or do a combination of train, bus, and subway. You'll lose 3 hours traveling from Seattle to Greenville due to the time zone difference. Traveling from Seattle in September, expect Greenville to be a bit warmer, temps between 83°F and 66°F. Wrap up your sightseeing on the 27th (Wed) early enough to drive to Myrtle Beach.
Find places to stay Sep 27 — 28:
Highlights from your trip
Myrtle Beach — 2 nights
©
Myrtle Beach is a coastal city on the east coast of the United States in Horry County, South Carolina. Start off your visit on the 28th (Thu): take in the architecture and atmosphere at St. John the Baptist Greek Orthodox Church, then get up close and personal with brilliant marine life at Ripley's Aquarium of Myrtle Beach, then get a taste of the local shopping with Broadway at the Beach, and finally make a trip to Myrtle Beach SkyWheel. Here are some ideas for day two: stop by Harrelson's Seafood Market, get a dose of the wild on a nature and wildlife tour, and then kick back and relax at Myrtle Beach.
For maps, other places to visit, reviews, and tourist information, read our Myrtle Beach trip planner.
Traveling by car from Greenville to Myrtle Beach takes 5 hours. Alternatively, you can fly; or take a bus. In September, daytime highs in Myrtle Beach are 83°F, while nighttime lows are 69°F. Finish your sightseeing early on the 29th (Fri) to allow enough time to drive to Charleston.
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For maps, other places to visit, reviews, and tourist information, read our Myrtle Beach trip planner.
Traveling by car from Greenville to Myrtle Beach takes 5 hours. Alternatively, you can fly; or take a bus. In September, daytime highs in Myrtle Beach are 83°F, while nighttime lows are 69°F. Finish your sightseeing early on the 29th (Fri) to allow enough time to drive to Charleston.
Side Trip
Find places to stay Sep 27 — 29:
Highlights from your trip
Charleston — 4 nights

Many visitors describe their Charleston holiday as a warm embrace by an old, dear friend--who lived about 200 years ago.Charleston is known for parks, historic sites, and sightseeing. Your trip includes some of its best attractions: take an in-depth tour of Fort Sumter National Monument, contemplate the long history of Nathaniel Russell House, tour the pleasant surroundings at Magnolia Plantation & Gardens, and browse the eclectic array of goods at Charleston City Market.
For reviews, photos, ratings, and other tourist information, read our Charleston online trip builder.
Traveling by car from Myrtle Beach to Charleston takes 2.5 hours. Alternatively, you can take a bus. In September in Charleston, expect temperatures between 84°F during the day and 70°F at night. Finish your sightseeing early on the 3rd (Tue) so you can drive to Hilton Head.
Find places to stay Sep 29 — Oct 3:
Highlights from your trip
Hilton Head — 1 night
©
A Hilton Head vacation may be heaven for a golfer, but the area also offers all kinds of other options for sports fans.On the 4th (Wed), hike along Hilton Head Island Bike Trails, enjoy the sand and surf at Coligny Beach, and then take a tour by water with Boat Tours & Water Sports.
For traveler tips, maps, ratings, and more tourist information, use the Hilton Head trip itinerary maker website.
Getting from Charleston to Hilton Head by car takes about 2.5 hours. Other options: take a bus. In October in Hilton Head, expect temperatures between 78°F during the day and 62°F at night. Wrap up your sightseeing on the 4th (Wed) early enough to fly back home.
Find places to stay Oct 3 — 4:
Highlights from your trip
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South Carolina travel guide
The Palmetto State
Composed of five distinct geographic regions with boundaries roughly parallel to the Atlantic coastline, South Carolina embraces rich history, scenic beauty, and outstanding cuisine. Originally established as a slave society dependent on the cultivation of rice and indigo, the state now boasts a diverse economy that includes massive production of textile goods, chemical products, machinery, and automobiles. Widely regarded as the beginning of the Deep South, the state remains a deeply conservative part of the country, fervently clinging to its religious and cultural traditions. South Carolinians are kind and open hosts to those who vacation here, eager to share the wealth of their cultural heritage with curious visitors. With many remarkable places to visit like Charleston and Hilton Head, your itinerary here is sure to be diverse and full of scenic attractions.