7 days in Florida Keys Itinerary

Created using Inspirock Florida Keys tour planner
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Key Largo
— 1 night
— 1 night
Key West
— 4 nights


Key Largo — 1 night

Diving Capital of the World

The northernmost island of the Florida Keys, Key Largo provides stunning scenery, a number of watersports opportunities, and plenty of areas to relax on vacation.
On the 3rd (Tue), do a tasting at Keys' Meads, get interesting insight from Capt. Sterling's Everglades Eco-Tours, and then get close to the beloved marine mammals with a swim-with-the-dolphins experience. Keep things going the next day: look for all kinds of wild species at Molasses Reef, then take a tour of African Queen Canal Cruise, then take an in-depth tour of History of Diving Museum, and finally look for all kinds of wild species at Florida Keys Wild Bird Rehabilitation Center.

To see photos, traveler tips, where to stay, and other tourist information, refer to the Key Largo trip itinerary builder tool.

Denver to Key Largo is an approximately 5.5-hour flight. You can also drive; or do a combination of bus and shuttle. The time zone changes from Mountain Standard Time (MST) to Eastern Standard Time (EST), which is usually a 2 hour difference. Prepare for much warmer weather when traveling from Denver in January: high temperatures in Key Largo hover around 75°F and lows are around 61°F. Wrap up your sightseeing on the 4th (Wed) to allow time to drive to Marathon.
Wildlife · Tours · Outdoors · Parks
Side Trip
Find places to stay Jan 3 — 4:

Marathon — 1 night

Heart of the Florida Keys

A tiny city just 16 km (10 mi) long, Marathon is spread across several islands in the middle of the Florida Keys.
On the 5th (Thu), look for all kinds of wild species at Dolphin Research Center, then examine the collection at Crane Point Museum & Nature Center, and then take in the views from Seven Mile Bridge.

To see reviews, ratings, and tourist information, go to the Marathon trip itinerary app.

Traveling by car from Key Largo to Marathon takes 1.5 hours. Alternatively, you can take a bus. In January, plan for daily highs up to 77°F, and evening lows to 66°F. Wrap up your sightseeing on the 5th (Thu) early enough to drive to Key West.
Parks · Wildlife · Museums
Find places to stay Jan 4 — 5:

Key West — 4 nights

Conch Republic

Located just 140 km (90 mi) from Cuba, Key West is an island only about 6.4 km (4 mi) long and 1.6 km (1 mi) wide.
You'll discover tucked-away gems like U.S. Coast Guard Cutter Ingham Maritime Museum and West Martello Tower. There's still lots to do: examine the collection at The Ernest Hemingway Home and Museum, take a tour by water with Boat Tours & Water Sports, contemplate the long history of Truman Little White House, and make a trip to Duval Street.

To find traveler tips, reviews, other places to visit, and more tourist information, you can read our Key West trip itinerary planner.

Getting from Marathon to Key West by car takes about 1.5 hours. Other options: take a bus. In January in Key West, expect temperatures between 76°F during the day and 66°F at night. Wrap up your sightseeing on the 9th (Mon) to allow time to fly back home.
Find places to stay Jan 5 — 9:

Florida Keys travel guide

An archipelago of about 1,700 islands extending in a gentle arc south and southwest of Florida's mainland, the Florida Keys divide the Atlantic from the Gulf of Mexico. Many visitors on vacation come to scuba dive in the coral reefs, fossilized and exposed as sea levels declined over thousands of years. In addition to being one of the world's top diving and fishing spots, the Keys feature hundreds of shops, restaurants, bars, and various tourist attractions, most of them crowded all year long with visitors on vacation. To soak up the Keys' atmosphere and discover writer Ernest Hemingway's former haunts, drive from one island to the other all the way to Key West, located just 140 km (90 mi) from Cuba.