60 days in South America & Central America Itinerary

60 days in South America & Central America Itinerary

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1
Lima, Peru
— 7 nights
Fly
2
Iquitos, Peru
— 4 nights
Fly
3
Guayaquil, Ecuador
— 5 nights
Fly
4
Quito, Ecuador
— 8 nights
Fly
5
Cali, Colombia
— 6 nights
Fly
6
Bogota, Colombia
— 6 nights
Fly
7
Medellin, Colombia
— 6 nights
Fly
8
Panama City, Panama
— 6 nights
Fly
9
Cartagena, Colombia
— 6 nights
Drive
10
Barranquilla, Colombia
— 4 nights

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Lima, Peru

— 7 nights

City of the Kings

Founded in 1535 by Spanish explorer Francisco Pizarro, Lima represents an interesting blend of modern attractions and preserved colonial architecture, much of it clustered in the World Heritage-listed city center.
Lima is known for museums, parks, and historic sites. Your plan includes some of its best attractions: get engrossed in the history at Museo Larco, delve into the distant past at Huaca Pucllana, take in the local highlights with Walking tours, and wander the streets of Barranco.

To find photos, reviews, and more tourist information, read our Lima travel planner.

If you are flying in from Brazil, the closest major aiport is Jorge Chávez International Airport. August in Lima sees daily highs of 22°C and lows of 18°C at night. Cap off your sightseeing on the 6th (Tue) early enough to catch the flight to Iquitos.

Things to do in Lima

Tours · Historic Sites · Museums · Parks
Find places to stay Aug 29 — Sep 6:
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Iquitos, Peru

— 4 nights

Capital of the Peruvian Amazon

The largest city in the Peruvian Amazon and the world's largest metropolis unreachable by road, Iquitos represents a major starting point for river and rainforest adventures.
Spend the 7th (Wed) wandering through the wild on a nature and wildlife tour. There's lots more to do: explore the activities along Amazon River, take a tour by water with Boat Tours & Water Sports, meet the residents at Quistococha Zoo, and don't miss a visit to Plaza de Armas de Iquitos.

To see photos, where to stay, other places to visit, and tourist information, read our Iquitos trip builder tool.

You can fly from Lima to Iquitos in 4 hours. Alternatively, you can do a combination of bus, car, and ferry. Traveling from Lima in September, expect nights in Iquitos to be a bit warmer, around 26°C, while days are much hotter, around 38°C. Finish up your sightseeing early on the 10th (Sat) so you can catch the flight to Guayaquil.

Things to do in Iquitos

Wildlife · Tours · Outdoors · Parks
Find places to stay Sep 6 — 10:
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Guayaquil, Ecuador

— 5 nights

Pearl of the Pacific

Hills dotted with colorful houses and waterfront promenades typify Guayaquil, Ecuador's largest city and commercial center.
Guayaquil is known for historic sites, parks, and shopping. Your plan includes some of its best attractions: take a stroll through Las Penas, get engrossed in the history at Museum of Anthropology and Contemporary Art, wander the wide-open spaces of Hacienda La Danesa, and see some colorful creatures with a scuba or snorkeling tour.

To see photos, reviews, where to stay, and tourist information, use the Guayaquil driving holiday planner.

Getting from Iquitos to Guayaquil by flight takes about 9 hours. Other options: do a combination of car, ferry, and bus; or do a combination of ferry and bus. Expect a daytime high around 36°C in September, and nighttime lows around 25°C. Finish your sightseeing early on the 15th (Thu) so you can fly to Quito.

Things to do in Guayaquil

Historic Sites · Wildlife · Parks · Neighborhoods
Find places to stay Sep 10 — 15:
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Quito, Ecuador

— 8 nights

Light of America

High in the Andean foothills, Quito remains one of the world's most photogenic capital cities, featuring two dramatic mountain ranges as its backdrop.
Explore Quito's surroundings by going to Pululahua Geobotanical Reserve (in Calacali), Otavalo (El Lechero & Peguche Wasi) and Cuicocha (in Cotacachi). On the 23rd (Fri), give your taste buds a day to remember with a local gastronomic tour. The adventure continues: take an in-depth tour of Museo Templo del Sol Pintor Ortega Maila, admire the landmark architecture of Fundacion Iglesia de la Compania, don't miss a visit to Independence Square, and contemplate in the serene atmosphere at Basilica del Voto Nacional.

For ratings, more things to do, other places to visit, and tourist information, read Quito online tour planner.

You can fly from Guayaquil to Quito in 2.5 hours. Other options are to drive; or take a bus. Expect a bit cooler temperatures when traveling from Guayaquil in September; daily highs in Quito reach 26°C and lows reach 15°C. Wrap up your sightseeing on the 23rd (Fri) to allow time to fly to Cali.

Things to do in Quito

Parks · Museums · Nature · Historic Sites

Side Trips

Find places to stay Sep 15 — 23:
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Cali, Colombia

— 6 nights

Salsa Capital of the World

Learning how to salsa may be the most popular thing to do in Cali, but this giant city in southwestern Colombia represents more than just the "Salsa Capital of the World." Home to over 2 million people, thriving Cali serves as a major commercial and industrial center in South America, boasting the fastest-growing economy in Colombia.
Get out of town with these interesting Cali side-trips: Catedral de Nuestra Senora del Rosario del Palmar (in Palmira) and Camino Real (in Barichara). The adventure continues: examine the collection at Museo Aereo Fenix, get up close to creatures of the deep with Trip Trip, steep yourself in history at Hacienda Canasgordas, and relax and rejuvenate at some of the top local wellness centers.

To see reviews, more things to do, ratings, and more tourist information, read our Cali online trip itinerary planner.

Getting from Quito to Cali by flight takes about 6 hours. Other options: take a bus; or drive. Traveling from Quito in September, expect Cali to be a bit warmer, temps between 37°C and 22°C. Wrap up your sightseeing on the 29th (Thu) early enough to fly to Bogota.

Things to do in Cali

Historic Sites · Wildlife · Outdoors · Tours

Side Trips

Find places to stay Sep 23 — 29:
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Bogota, Colombia

— 6 nights

Athens of South America

Colombia's heart and soul, Bogota has earned the nickname "Athens of South America" thanks to its abundance of universities, libraries, and lower-level schools.
Explore Bogota's surroundings by going to Zipaquira (Museo Arqueologico de Zipaquira, Catedral de Sal de Zipaquira, &more) and Laguna de Guatavita (in Tierra Negra). The adventure continues: see the interesting displays at Gold Museum (Museo del Oro), make a trip to Bolivar Square, indulge in some culinary diversions at a local gastronomic tour, and explore the world behind art at Museo Santa Clara.

To find reviews, ratings, and other tourist information, use the Bogota route website.

You can fly from Cali to Bogota in 3 hours. Other options are to drive; or do a combination of bus and taxi. Traveling from Cali in September, you will find days in Bogota are cooler (22°C), and nights are slightly colder (9°C). Cap off your sightseeing on the 5th (Wed) early enough to catch the flight to Medellin.

Things to do in Bogota

Outdoors · Parks · Nature · Museums

Side Trips

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Medellin, Colombia

— 6 nights

City of the Eternal Spring

Nestled between rising hills in a narrow valley, Medellin serves as an energetic melting pot of people from all socio-economic classes.
Medellin is known for parks, museums, and zoos & aquariums. Your plan includes some of its best attractions: take in the local highlights with Walking tours, glide through the air with a parasailing or paragliding tour, see Off-Road Tours, and observe the fascinating underwater world at Parque Explora.

To find more things to do, ratings, where to stay, and other tourist information, go to the Medellin trip itinerary planner.

Fly from Bogota to Medellin in 2.5 hours. Alternatively, you can drive; or take a bus. Plan for a bit warmer temperatures traveling from Bogota in October, with highs in Medellin at 32°C and lows at 20°C. Finish up your sightseeing early on the 11th (Tue) so you can catch the flight to Panama City.

Things to do in Medellin

Parks · Tours · Wildlife · Outdoors

Side Trip

Find places to stay Oct 5 — 11:
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Panama City, Panama

— 6 nights

Dubai of Latin America

Arguably the most modern of Central American cities, Panama City boasts a shimmering skyline of glass skyscrapers.
Panama City is known for historic sites, shopping, and museums. Your plan includes some of its best attractions: don't miss a visit to Panama Canal, admire nature's wide array of creatures at Summit Botanical Gardens, examine the collection at Biomuseo, and explore the wealth of natural beauty at Metropolitan National Park.

For more things to do, maps, other places to visit, and other tourist information, go to the Panama City trip itinerary planner.

Traveling by flight from Medellin to Panama City takes 4.5 hours. Alternatively, you can do a combination of bus, ferry, and taxi; or do a combination of bus and ferry. Traveling from Medellin in October, expect Panama City to be somewhat warmer, temps between 36°C and 28°C. Wrap up your sightseeing on the 17th (Mon) to allow time to fly to Cartagena.

Things to do in Panama City

Historic Sites · Parks · Neighborhoods · Nature
Find places to stay Oct 11 — 17:
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Cartagena, Colombia

— 6 nights

City of Heroes

The site of the continent's first Spanish colony, Cartagena retains much of its colonial flavor thanks to a World Heritage-listed old town, encircled by old walls and protected by imposing fortresses.
Change things up with a short trip to Playa Blanca in Isla Baru (about 1h 5 min away). There's much more to do: step into the grandiose world of Castillo de San Felipe de Barajas, steep yourself in history at Walled City of Cartagena, don't miss a visit to Plaza Santo Domingo, and take in the architecture and atmosphere at Sanctuary of Saint Peter Claver.

For traveler tips, where to stay, other places to visit, and other tourist information, you can read our Cartagena trip itinerary planning site.

You can fly from Panama City to Cartagena in 4.5 hours. In October, daily temperatures in Cartagena can reach 38°C, while at night they dip to 30°C. Finish your sightseeing early on the 24th (Mon) so you can take a bus to Barranquilla.

Things to do in Cartagena

Historic Sites · Tours · Parks · Outdoors

Side Trip

Find places to stay Oct 17 — 24:
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Barranquilla, Colombia

— 4 nights

Golden Gate of Colombia

An industrial port city on Colombia's Caribbean coast, Barranquilla represents the fourth-most populous city in the country.
When in Barranquilla, make a side trip to see Castillo de Salgar in Puerto Colombia, approximately Puerto Colombia away. The adventure continues: pause for some photo ops at Monumento Ventana Al Mundo, wander the streets of El Prado, get advice or help at Biblioteca Piloto del Caribe, and pause for some serene contemplation at Catedral Metropolitana Maria Reina de Barranquilla.

For ratings, reviews, more things to do, and other tourist information, read Barranquilla trip planner.

Traveling by bus from Cartagena to Barranquilla takes 2.5 hours. Alternatively, you can drive. In October, plan for daily highs up to 38°C, and evening lows to 28°C.

Things to do in Barranquilla

Historic Sites · Museums · Shopping · Parks

Side Trip

Find places to stay Oct 24 — 28:
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