60 days in Medellin, Quito & Mexico City Itinerary

60 days in Medellin, Quito & Mexico City Itinerary

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Medellin, Colombia
— 13 nights
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Quito, Ecuador
— 23 nights
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Mexico City, Mexico
— 23 nights

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Medellin, Colombia

— 13 nights

City of the Eternal Spring

Nestled between rising hills in a narrow valley, Medellin serves as an energetic melting pot of people from all socio-economic classes.
Change things up with a short trip to Piedra Del Penol in Guatape (about 1h 50 min away). On the 10th (Thu), give your taste buds a day to remember with a local gastronomic tour. There's still lots to do: get the lay of the land with Walking tours, contemplate the waterfront views at Laguna de Guatape, fly like a bird with a parasailing or paragliding tour, and see Off-Road Tours.

Quickly create a custom-made itinerary for Medellin using our trip planner.

Mexico City, Mexico to Medellin is an approximately 8-hour flight. The time zone difference when traveling from Mexico City to Medellin is 1 hour. Traveling from Mexico City in February, things will get somewhat warmer in Medellin: highs are around 32°C and lows about 20°C. Cap off your sightseeing on the 23rd (Wed) early enough to catch the flight to Quito.

Things to do in Medellin

Tours · Parks · Outdoors · Museums

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Quito, Ecuador

— 23 nights

Light of America

High in the Andean foothills, Quito remains one of the world's most photogenic capital cities, featuring two dramatic mountain ranges as its backdrop.
Venture out of the city with trips to Quitsato (in Cayambe), Cascada de Peguche (in Peguche) and Cuicocha (in Cotacachi). On the 18th (Fri), give your taste buds a day to remember with a local gastronomic tour. On the 27th (Sun), spend a fun day on foot with Walking tours. There's lots more to do: take in the spiritual surroundings of Fundacion Iglesia de la Compania, gain insight at La Ronda, admire the landmark architecture of Iglesia y Convento de San Francisco, and browse the eclectic array of goods at Otavalo Market.

To see reviews, other places to visit, traveler tips, and more tourist information, read Quito road trip planning tool.

Traveling by flight from Medellin to Quito takes 6.5 hours. Alternatively, you can drive; or take a bus. Plan for little chillier temperatures traveling from Medellin in February, with highs in Quito at 24°C and lows at 16°C. Cap off your sightseeing on the 18th (Fri) early enough to catch the flight to Mexico City.

Things to do in Quito

Parks · Museums · Nature · Tours

Side Trips

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Mexico City, Mexico

— 23 nights

City of Palaces

Breathtakingly large, Mexico City provides a home for almost 9 million people living in nearly 1,700 distinct neighborhoods.
Venture out of the city with trips to Palacio de Gobierno del Estado de Tlaxcala (in Tlaxcala), Tepozteco (in Tepoztlan) and San Juan Teotihuacan (Piramide de la Serpiente Emplumada, Zona Arqueológica de Teotihuacan Estacionamiento Puerta 5, &more). There's much more to do: take an in-depth tour of Museo Nacional de Antropologia, browse the exhibits of Museo Frida Kahlo, explore the ancient world of Museo del Templo Mayor, and take in the spiritual surroundings of Metropolitan Cathedral (Catedral Metropolitana).

For photos, traveler tips, more things to do, and tourist information, go to the Mexico City trip planner.

You can fly from Quito to Mexico City in 8 hours. The time zone difference moving from Ecuador Time to Central Standard Time is minus 1 hour. Expect slightly colder evenings in Mexico City when traveling from Quito in March, with lows around 12°C. Finish up your sightseeing early on the 10th (Sun) so you can travel back home.

Things to do in Mexico City

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