49 days in Central America Itinerary

49 days in Central America Itinerary

Created using Inspirock Central America vacation builder

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Route & dates

49 days in Central America Itinerary

Start: London, United Kingdom
Fly + shuttle:  17​h 45​min
1
Antigua, Guatemala
— 10 nights
shuttle + Fly:  6​h 15​min
2
Utila, Honduras
— 6 nights
Fly + bus:  9​h 15​min
3
Leon, Nicaragua
— 2 nights
Drive:  2​h 15​min
4
Granada, Nicaragua
— 2 nights
Drive:  4​h 30​min
5
La Fortuna de San Carlos, Costa Rica
— 6 nights
Drive:  2​h
6
Monteverde, Costa Rica
— 5 nights
Drive:  2​h 30​min
7
San Jose, Costa Rica
— 4 nights
+2
bus + Drive + ferry:  1​h 45​min
8
Bocas Town, Panama
— 3 nights
ferry + Drive:  3​h 45​min
9
Boquete, Panama
— 6 nights
+2
bus + taxi + Fly:  2​h 15​min
10
Panama City, Panama
— 3 nights
End: Panama City, Panama

10
nights
Antigua, Guatemala

Antigua ©
The former capital of Guatemala and a World Heritage Site, Antigua retains its colonial charm and remains one of the most visited destinations in the country.
Popular historic sites such as Iglesia de la Merced and Convento de las Capuchinas are in your itinerary. Get some cultural insight at Volcán Pacaya and Casa Santo Domingo Museums. Take a break from Antigua with a short trip to La Ruta del Yalu in Sumpango, about 48 minutes away. There's lots more to do: explore the ancient world of Church of San Francisco, contemplate the long history of Casa Popenoe, stop by Nim Po't Centro de Textiles Tradicionales, and make a trip to The Plaza Central Park.

To see where to stay, other places to visit, maps, and other tourist information, read Antigua trip planner.

London, UK to Antigua is an approximately 18-hour combination of flight and bus. You can also do a combination of flight, car, bus, and shuttle. The time zone difference when traveling from London to Antigua is minus 6 hours. In May, Antigua is a bit warmer than London - with highs of 30°C and lows of 19°C. Wrap up your sightseeing on the 24th (Fri) early enough to travel to Utila.

Things to do in Antigua

Historic Sites Parks Outdoors

Side Trips

La Ruta del Yalu, Valhalla Experimental Station
Find places to stay May 14 — 24:
Highlights from your plan
Convento Santa Clara ©
Convento Santa Clara
Iglesia de La Merced ©
Iglesia de La Merced
Volcán Pacaya ©
Volcán Pacaya

6
nights
Utila, Honduras

The island of Utila has become known as a good place to learn how to dive in Latin America.
Get in touch with nature at Scuba & Snorkeling and Iguana Research & Breeding Station. Explore hidden gems such as Utila Cays and Wei Bodywork massage - CLOSED. There's more to do: relax and rejuvenate at some of the top local wellness centers and enjoy the sand and surf at Beach Buns Fitness & Yoga - CLOSED.

For maps, reviews, traveler tips, and more tourist information, go to the Utila online trip itinerary builder .

Traveling by combination of bus and flight from Antigua to Utila takes 6.5 hours. Alternatively, you can do a combination of shuttle and bus; or take a bus. Expect somewhat warmer temperatures when traveling from Antigua in May; daily highs in Utila reach 36°C and lows reach 26°C. You'll set off for Leon on the 30th (Thu).

Things to do in Utila

Wildlife Parks Adventure
Find places to stay May 24 — 30:
Highlights from your plan
Scuba & Snorkeling
Utila Cays Diving ©
Utila Cays Diving
Iguana Research & Breeding Station ©
Iguana Research & Breeding Station

2
nights
Leon, Nicaragua

Leon ©
A cultured and storied city, Leon attracts guests from all over the world, drawn to the second city's style, thriving intellectual life, and liveliness.
Start off your visit on the 31st (Fri): identify plant and animal life at Juan Venado Island Nature Reserve and then see the interesting displays at Museo Ruben Dario. Get ready for a full day of sightseeing on the next day: contemplate in the serene atmosphere at El Calvario Church, then take in the architecture and atmosphere at Church The Recollection, then examine the collection at Museo de Arte Fundacion Ortiz-Gurdian, and finally take in the architecture and atmosphere at Catedral de la Asunción.

To see more things to do, reviews, and more tourist information, you can read our Leon travel itinerary planner .

Do a combination of flight and bus from Utila to Leon in 9.5 hours. Alternatively, you can do a combination of flight and shuttle; or take a bus. Expect somewhat warmer evenings in Leon when traveling from Utila in May, with lows around 30°C. On the 2nd (Sun), wrap the sightseeing up by early afternoon so you can drive to Granada.

Things to do in Leon

Museums Historic Sites Wildlife

Side Trips

Juan Venado Island Nature Reserve, Flor de Cana Tour
Find places to stay May 30 — Jun 2:
Highlights from your plan
Catedral de la Asunción ©
Catedral de la Asunción
Juan Venado Island Nature Reserve ©
Juan Venado Island Nature Reserve

2
nights
Granada, Nicaragua

Granada ©
The lakeside city of Granada has the look and feel of a historically important economic and political center, with grand colonial architecture, a unified look, and many cultural attractions.
Kick off your visit on the 2nd (Sun): view the masterpieces at Galeria Mi Camara Mi Mundo and then take in the architecture and atmosphere at Catedral de Granada.

To see photos, reviews, traveler tips, and tourist information, you can read our Granada trip itinerary planner.

You can drive from Leon to Granada in 2.5 hours. Other options are to take a shuttle; or take a bus. In June in Granada, expect temperatures between 38°C during the day and 28°C at night. Finish your sightseeing early on the 4th (Tue) to allow enough time to drive to La Fortuna de San Carlos.

Things to do in Granada

Wildlife Parks Historic Sites
Find places to stay Jun 2 — 4:
Highlights from your plan
Nicaragua Butterfly Reserve ©
Nicaragua Butterfly Reserve
Iglesia de La Merced ©
Iglesia de La Merced
Catedral de Granada ©
Catedral de Granada

6
nights
La Fortuna de San Carlos, Costa Rica

La Fortuna de San Carlos ©
Set against the backdrop of the imposing Arenal Volcano, La Fortuna de San Carlos offers visitors a chance to explore diverse natural landscapes and sample some delicious local produce.
Step off the beaten path and head to Butterfly Conservatory and Paradise Hot Springs. Get in touch with nature at Arenal Natura Ecological Park and River Rafting & Tubing. Change things up with a short trip to Catedral de Ciudad Quesada in Quesada (about 1h 15 min away). There's lots more to do: witness a stunning natural landmark at Tabacon Hot Springs, take in the dramatic scenery at La Fortuna Waterfall, explore the fascinating underground world of Venado Caves, and head outdoors with Salto.

To find ratings and more tourist information, go to the La Fortuna de San Carlos driving holiday planner.

Getting from Granada to La Fortuna de San Carlos by car takes about 4.5 hours. Other options: do a combination of shuttle, bus, and taxi; or take a bus. Finish your sightseeing early on the 10th (Mon) so you can drive to Monteverde.

Things to do in La Fortuna de San Carlos

Parks Nature Wildlife

Side Trips

Arenal Volcano National Park, Butterfly Conservatory, Catedral de Ciudad Quesada
Find places to stay Jun 4 — 10:
Highlights from your plan
Tabacon Hot Springs ©
Tabacon Hot Springs
Butterfly Conservatory ©
Butterfly Conservatory
River Rafting & Tubing

5
nights
Monteverde, Costa Rica

Monteverde ©
Monteverde is all about natural attractions, not surprising for an eco-tourism hotspot known for its cloud forests and rich diversity of animal life.
Explore hidden gems such as Reserva Bosque Nuboso Santa Elena and Ecological Sanctuary. Step out of the city life by going to Monteverde Cloud Forest Biological Reserve and Zipline. Spend the 12th (Wed) exploring nature at Up in the Cloud Forest. There's much more to do: admire nature's wide array of creatures at The Bat Jungle, identify plant and animal life at Valle Escondido Preserve, and stop by Souvenir Rosewood.

To see other places to visit, where to stay, maps, and other tourist information, refer to the Monteverde road trip planning tool .

Getting from La Fortuna de San Carlos to Monteverde by car takes about 2 hours. Wrap up your sightseeing by early afternoon on the 15th (Sat) to allow time for the car ride to San Jose.

Things to do in Monteverde

Parks Wildlife Nature
Find places to stay Jun 10 — 15:
Highlights from your plan
Reserva Bosque Nuboso Santa Elena ©
Reserva Bosque Nuboso Santa Elena
Zipline

4
nights
San Jose, Costa Rica

San Jose ©
A trip to San Jose, the capital, commercial center, and cultural hub of Costa Rica, gives you a chance to experience the lively atmosphere and rich cultural past of this vibrant country.
Deepen your sense of the past at sights like Our Lady of the Angels Basilica (Basilica de Nuestra Senora de Los Angeles) and Iglesia de San Jose de Orosi and the Museum. Get outdoors at La Paz Waterfall Gardens and Poas Volcano. Get out of town with these interesting San Jose side-trips: Ruins of the Church of Carthage (in Cartago) and Souvenir Museum (in Alajuela). There's more to do: get engrossed in the history at National Museum (Museo Nacional) and look for gifts at Chieton Moren.

To see other places to visit, more things to do, photos, and more tourist information, refer to the San Jose trip itinerary planning site .

Traveling by car from Monteverde to San Jose takes 2.5 hours. Alternatively, you can do a combination of taxi and flight; or take a bus. June in San Jose sees daily highs of 31°C and lows of 23°C at night. Finish your sightseeing early on the 19th (Wed) so you can travel to Bocas Town.

Things to do in San Jose

Parks Nature Museums

Side Trips

Cartago, Poas Volcano, Iglesia de San Jose de Orosi and the Museum, Riish and Toosh Afro Costa Rican Paintings, Souvenir Museum
Find places to stay Jun 15 — 19:
Highlights from your plan

3
nights
Bocas Town, Panama

The colorful and relaxed Bocas Town has a welcoming atmosphere, with the modestly sized urban area showcasing typical Caribbean clapboard houses and home to a mixed community from across the world.
Step out of the city life by going to Boca del Drago and Scuba & Snorkeling. Discover out-of-the-way places like Finca Los Monos Botanical Garden and Smithsonian Tropical Research Institute. Step out of Bocas Town to go to Changuinola and see Aamvecona, which is approximately 1h 55 min away.

To see maps, other places to visit, ratings, and tourist information, you can read our Bocas Town trip itinerary planner .

You can do a combination of shuttle and flight from San Jose to Bocas Town in 2 hours. Other options are to do a combination of bus, car, and ferry; or take a shuttle. Due to the time zone difference, you'll lose 1 hour traveling from San Jose to Bocas Town. Traveling from San Jose in June, Bocas Town is somewhat warmer at night with lows of 30°C. On the 22nd (Sat), wrap the sightseeing up by early afternoon so you can travel to Boquete.

Things to do in Bocas Town

Outdoors Wildlife Adventure

Side Trips

Aamvecona, Finca Los Monos Botanical Garden
Find places to stay Jun 19 — 22:
Highlights from your plan
Scuba & Snorkeling
Aamvecona ©
Aamvecona
Boca del Drago ©
Boca del Drago

6
nights
Boquete, Panama

Boquete ©
Now known internationally for its fresh mountain air, year-round pleasant temperatures, and large community of North American expats, Boquete has changed rapidly since the start of the century, changing from a humble mountain town, into a humble mountain surrounded by gated communities and estates.
Take a break from the city and head to Sendero Los Quetzales (The Quetzales Trail) and Jungla de Panama Wildlife Refuge. Discover out-of-the-way places like Spas & Wellness and Los Cangilones de Gualaca. You'll find plenty of places to visit near Boquete: Volcan (Lagunas Adventures on The Janson Coffee Farm & Sitio Barriles Museum) and Catedral San Jose De David (in David). And it doesn't end there: explore by horseback at Franklin's Horseback Riding, take a memorable tour with Tours, look for gifts at Up In The Hill, and hunt for treasures at Boquete Tuesday Market.

To find reviews, traveler tips, photos, and tourist information, use the Boquete road trip app .

Do a combination of ferry and car from Bocas Town to Boquete in 4 hours. Alternatively, you can take a shuttle. Traveling from Bocas Town in June, you will find days in Boquete are a bit warmer (36°C), and nights are about the same (28°C). On the 28th (Fri), wrap the sightseeing up by early afternoon so you can travel to Panama City.

Things to do in Boquete

Outdoors Parks Tours

Side Trips

Volcan, Catedral San Jose De David, Los Cangilones de Gualaca, Up In The Hill
Find places to stay Jun 22 — 28:
Highlights from your plan
Franklin's Horseback Riding ©
Franklin's Horseback Riding
Los Cangilones de Gualaca ©
Los Cangilones de Gualaca

3
nights
Panama City, Panama

Panama City ©
Arguably the most modern of Central American cities, Panama City boasts a shimmering skyline of glass skyscrapers.
You'll explore the less-touristy side of things at Iglesia del Carmen and Nature & Wildlife Tours. Get a sense of the local culture at Casco Viejo and Iglesia de San Francisco de Asis. There's more to do: take an in-depth tour of Museo del Canal Interoceanico de Panama and explore the striking landscape of Soberania National Park.

To see where to stay, ratings, traveler tips, and tourist information, read our Panama City trip itinerary maker website .

Traveling by combination of taxi and flight from Boquete to Panama City takes 2.5 hours. Alternatively, you can do a combination of car and flight; or drive. Expect a daytime high around 36°C in June, and nighttime lows around 28°C. Finish your sightseeing early on the 1st (Mon) to allow enough time to travel back home.

Things to do in Panama City

Wildlife Outdoors Tours

Side Trip

Nature & Wildlife Tours
Find places to stay Jun 28 — Jul 1:
Highlights from your plan
Casco Viejo ©
Casco Viejo
Iglesia del Carmen ©
Iglesia del Carmen
Soberania National Park ©
Soberania National Park

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