46 days in Sicily Itinerary

46 days in Sicily Itinerary

Created using Inspirock Italy trip itinerary planner

Make it your trip
1
Catania
— 4 nights
Drive
2
Palermo
— 4 nights
Drive
3
San Vito lo Capo
— 2 nights
Drive
4
Calatafimi-Segesta
— 1 night
Drive
5
Trapani
— 4 nights
Drive
6
Marsala
— 2 nights
Drive
7
Sciacca
— 3 nights
Drive
8
Agrigento
— 2 nights
Drive
9
Enna
— 3 nights
Drive
10
Troina
Drive
11
Ragusa
— 3 nights
Drive
12
Noto
— 3 nights
Drive
13
Syracuse
— 4 nights
Drive
14
Taormina
— 2 nights
Drive
15
Castiglione di Sicilia
— 2 nights
Drive
16
Messina
— 2 nights
Bus to Milazzo, Ferry to Lipari
17
Lipari
— 2 nights
Ferry to Milazzo, Train to Cefalu
18
Cefalu
— 2 nights
Drive

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Catania

— 4 nights

Black Pearl of Ionian Sea

The landscape surrounding Catania, a medieval city on Sicily's eastern coast, is dominated by Mount Etna, the tallest active volcano in Europe.
Catania is known for nature, historic sites, and museums. Your trip includes some of its best attractions: take your sightseeing to a higher altitude at Mt Etna, trek along Etnatao Etna Excursions, take in the spiritual surroundings of Basilica Catedrale Sant'Agata V.M. Catania, and admire the natural beauty at Giardino Bellini.

Find out how to plan Catania trip without stress by asking Inspirock to help create an itinerary.

If you are flying in from United States, the closest major aiports are Catania-Fontanarossa Airport and Comiso Airport. Finish up your sightseeing early on the 3rd (Mon) so you can go by car to Palermo.

Things to do in Catania

Parks · Outdoors · Tours · Nature
Find places to stay Sep 29 — Oct 3:
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Palermo

— 4 nights
The capital of Sicily, Palermo was founded by the Phoenicians under the name of Ziz.
Go for a jaunt from Palermo to Monreale to see Duomo di Monreale about 32 minutes away. There's still lots to do: pause for some serene contemplation at Cattedrale di Palermo, indulge your taste buds at Food & Drink, admire the landmark architecture of Norman Palace, and kick back and relax at Spiaggia di Mondello.

For other places to visit, where to stay, photos, and tourist information, read our Palermo trip itinerary planner.

Drive from Catania to Palermo in 2.5 hours. Alternatively, you can take a bus; or take a train. You will leave for San Vito lo Capo on the 7th (Fri).

Things to do in Palermo

Historic Sites · Tours · Parks · Outdoors

Side Trip

Find places to stay Oct 3 — 7:
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San Vito lo Capo

— 2 nights
A vacation in San Vito lo Capo offers a chance to enjoy a sheltered bay and a town with distinctive Arab-Norman architecture.
Start off your visit on the 7th (Fri): kick back and relax at Spiaggia di Macari and then get a new perspective on things with Boat Tours & Water Sports. Get ready for a full day of sightseeing on the next day: stroll through Riserva Naturale Dello Zingaro.

For more things to do, where to stay, traveler tips, and more tourist information, go to the San Vito lo Capo online trip builder.

Getting from Palermo to San Vito lo Capo by car takes about 2 hours. Other options: do a combination of train and taxi; or take a bus. In October, daytime highs in San Vito lo Capo are 75°F, while nighttime lows are 64°F. Finish your sightseeing early on the 9th (Sun) so you can drive to Calatafimi-Segesta.

Things to do in San Vito lo Capo

Parks · Wildlife · Outdoors · Tours

Side Trip

Find places to stay Oct 7 — 9:
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Calatafimi-Segesta

— 1 night
Calatafimi-Segesta is a small town, more popularly known simply as Calatafimi, in the Province of Trapani, in Sicily, southern Italy.The full name of the municipality was created in 1997 and is meant to highlight the presence within its territory of the 5th century B.C. Doric temple of Segesta, widely regarded as one of the most intact of its type. On the 9th (Sun), make a trip to Parco Archeologico and then explore the ancient world of Tempio di Segesta.

To find where to stay, photos, ratings, and other tourist information, refer to the Calatafimi-Segesta road trip tool.

Getting from San Vito lo Capo to Calatafimi-Segesta by car takes about 1.5 hours. Other options: do a combination of bus and taxi. In October, daily temperatures in Calatafimi-Segesta can reach 77°F, while at night they dip to 61°F. You'll set off for Trapani on the 10th (Mon).

Things to do in Calatafimi-Segesta

Historic Sites
Find places to stay Oct 9 — 10:
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Highlights from your trip

Trapani

— 4 nights

City of Two Seas

Historically known for its importance in salt production, Trapani has gained recognition as an enticing but affordable vacation locale in Sicily.
Trapani is known for parks, historic sites, and outdoors. Your trip includes some of its best attractions: look for gifts at La Pasticceria Maria Grammatico, pause for some photo ops at Monumento A Giuseppe Garibaldi, make a trip to Chiesa Madre - Duomo di Erice, and Head underground at Grotta Mangiapane.

For traveler tips, reviews, photos, and more tourist information, use the Trapani vacation maker app.

You can drive from Calatafimi-Segesta to Trapani in an hour. Alternatively, you can take a bus. October in Trapani sees daily highs of 77°F and lows of 61°F at night. On the 14th (Fri), you're off to Marsala.

Things to do in Trapani

Parks · Historic Sites · Outdoors · Tours

Side Trips

Find places to stay Oct 10 — 14:
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Marsala

— 2 nights
Marsala is an Italian town located in the Province of Trapani in the westernmost part of Sicily. On the 14th (Fri), stroll through Isola di Mozia (Mothia)/ San Pantaleo and then identify plant and animal life at SEI - Saline Ettore E Infersa. Here are some ideas for day two: head outdoors with Outdoor Activities and then see the interesting displays at Museo Archeologico Baglio Anselmi.

Plan my Marsala trip by asking Inspirock to come up with tips and suggestions.

Drive from Trapani to Marsala in an hour. Alternatively, you can take a train; or take a bus. In October, daytime highs in Marsala are 77°F, while nighttime lows are 61°F. On the 16th (Sun), you'll travel to Sciacca.

Things to do in Marsala

Parks · Outdoors · Tours · Nature
Find places to stay Oct 14 — 16:
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Sciacca

— 3 nights
Sciacca, also Schiacca, is a town and comune in the province of Agrigento on the southwestern coast of Sicily. Explore the numerous day-trip ideas around Sciacca: Montevago (Terme Acqua Pia & Amodeo's Farm - Olive Oil Producers in Sicily) and Pensiero Contemporaneo (in Marinella di Selinunte). Next up on the itinerary: examine the collection at Casa Museo del Sapone, don't miss a visit to Piazza Angelo Scandaliato, and explore the galleries of Il Castello Incantato.

For ratings, traveler tips, other places to visit, and tourist information, you can read our Sciacca day trip planning website.

You can drive from Marsala to Sciacca in 1.5 hours. Alternatively, you can take a bus. Wrap up your sightseeing on the 19th (Wed) to allow time to drive to Agrigento.

Things to do in Sciacca

Museums · Wineries · Spas · Shopping

Side Trips

Find places to stay Oct 16 — 19:
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Agrigento

— 2 nights

Valley of the Temples

Historically one of ancient Greece's leading cities, Sicily's Agrigento is home to the seven monumental temples that make up the well-preserved Valley of the Temples.
Kick off your visit on the 19th (Wed): get engrossed in the history at Museo Archeologico Regionale di Agrigento and then contemplate in the serene atmosphere at Valle dei Templi. Get ready for a full day of sightseeing on the 20th (Thu): take in the spiritual surroundings of Santuario di San Calogero, then take in nature's colorful creations at Il Giardino della Kolymbethra, and then take in the dramatic natural features at Scala dei Turchi.

To find photos, where to stay, other places to visit, and other tourist information, use the Agrigento road trip planning tool.

Traveling by car from Sciacca to Agrigento takes an hour. Alternatively, you can take a bus. In October in Agrigento, expect temperatures between 76°F during the day and 67°F at night. Finish your sightseeing early on the 21st (Fri) to allow enough time to drive to Enna.

Things to do in Agrigento

Historic Sites · Parks · Nature · Museums

Side Trip

Find places to stay Oct 19 — 21:
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Enna

— 3 nights
Enna is a city and comune located roughly at the center of Sicily, southern Italy, in the province of Enna, towering above the surrounding countryside. Enna is known for historic sites, outdoors, and nature. Your trip includes some of its best attractions: take in the spiritual surroundings of Santuario del SS. Crocifisso di Papardura, take in panoramic vistas at Torre di Federico II, examine the collection at Regional Museum of Enna interdisciplinary, and admire the verdant scenery at Rocca di Cerere.

To see ratings, photos, and more tourist information, use the Enna online holiday planner.

You can drive from Agrigento to Enna in 1.5 hours. Finish your sightseeing early on the 24th (Mon) to allow enough time to travel to Troina.

Things to do in Enna

Historic Sites · Parks · Outdoors · Nature
Find places to stay Oct 21 — 24:
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Troina

Troina is a town, former bishopric, comune and Latin Catholic titular see in the province of Enna, Sicily, Italy. On the 24th (Mon), explore the historical opulence of Castello di Gagliano Castelferrato.

Planning Troina trip won't be overwhelming when you use Inspirock's itinerary maker.

You can drive from Enna to Troina in 2 hours. Wrap up your sightseeing by early afternoon on the 24th (Mon) to allow time for travel to Ragusa.

Things to do in Troina

Historic Sites

Side Trip

Find places to stay Oct 24 — 25:
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Ragusa

— 3 nights

Town of Bridges

Once a flourishing ancient city, Ragusa was rebuilt after a devastating earthquake in 1693.
Take a break from Ragusa with a short trip to Centro storico di Scicli - World Heritage Site in Scicli, about 38 minutes away. And it doesn't end there: appreciate the extensive heritage of Ragusa Ibla, pause for some serene contemplation at Cathedral of St. George, take in nature's colorful creations at Giardini Iblei, and admire the landmark architecture of Saint Giorgio.

To find photos, maps, traveler tips, and other tourist information, read our Ragusa online trip itinerary planner.

You can drive from Troina to Ragusa in 3 hours. October in Ragusa sees daily highs of 77°F and lows of 59°F at night. Cap off your sightseeing on the 27th (Thu) early enough to go by car to Noto.

Things to do in Ragusa

Historic Sites · Parks · Shopping

Side Trips

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Noto

— 3 nights
Noto is a city and comune in the Province of Syracuse, Sicily, Italy. On the 28th (Fri), contemplate in the serene atmosphere at Chiesa di San Carlo Borromeo, then take in the spiritual surroundings of St. Nicholas Cathedral, and then get to know the fascinating history of Centro Storico. Get ready for a full day of sightseeing on the 29th (Sat): look for gifts at Adelfio - Marzamemi, stroll through Riserva Naturale Orientata Oasi faunistica di Vendicari, and then appreciate the extensive heritage of Corso Vittorio Emanuele III.

To see other places to visit, maps, ratings, and tourist information, refer to the Noto travel route planner.

Getting from Ragusa to Noto by car takes about 1.5 hours. Other options: take a train; or take a bus. Cap off your sightseeing on the 30th (Sun) early enough to go by car to Syracuse.

Things to do in Noto

Historic Sites · Parks · Shopping · Wildlife

Side Trip

Find places to stay Oct 27 — 30:
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Syracuse

— 4 nights

Pearl of the Mediterranean

Philosopher Cicero once described Syracuse as "the greatest Greek city and the most beautiful of them all." A powerful city-state of ancient Greece, Syracuse now is the capital of the eponymous Italian province on the eastern coast of Sicily.
Syracuse is known for nature, historic sites, and beaches. Your trip includes some of its best attractions: head off the coast to Ortigia, pause for some serene contemplation at Chiesa di San Giovanni Alle Catacombe, delve into the distant past at Teatro Greco, and take an in-depth tour of Museo Archeologico Regionale Paolo Orsi.

For traveler tips, photos, other places to visit, and more tourist information, you can read our Syracuse online tour planner.

You can drive from Noto to Syracuse in an hour. Alternatively, you can take a train; or take a bus. Finish your sightseeing early on the 3rd (Thu) to allow enough time to drive to Taormina.

Things to do in Syracuse

Parks · Historic Sites · Outdoors · Nature
Find places to stay Oct 30 — Nov 3:
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Taormina

— 2 nights
With its warm island weather and cliffside location overlooking the Ionion Sea, Taormina has been one of Sicily's most popular getaway destinations since the early 19th century.
Start off your visit on the 3rd (Thu): head off the coast to Isola Bella, then take in the architecture and atmosphere at Santa Caterina Church, then don't miss a visit to Ancient Theatre of Taormina, and finally walk around Villa Comunale. On the 4th (Fri), you'll have a packed day of sightseeing: don't miss a visit to Corso Umberto, then take in the pleasant sights at Piazza IX Aprile, and then get a new perspective on things with Blue Sea Diving Center.

To find traveler tips, where to stay, other places to visit, and tourist information, read our Taormina trip planner.

You can drive from Syracuse to Taormina in 1.5 hours. Alternatively, you can take a train; or take a bus. In November, daily temperatures in Taormina can reach 68°F, while at night they dip to 57°F. Wrap up your sightseeing on the 5th (Sat) early enough to drive to Castiglione di Sicilia.

Things to do in Taormina

Outdoors · Parks · Tours · Wildlife
Find places to stay Nov 3 — 5:
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Castiglione di Sicilia

— 2 nights
Start off your visit on the 5th (Sat): tour the pleasant surroundings at Le Gole dell'Alcantara and then explore the stunning scenery at Gole Alcantara Botanical and Geological Park. On the 6th (Sun), you'll have a packed day of sightseeing: learn about winemaking at Gambino Vini and then hike along Etna Donkey Trekking.

To find reviews, ratings, traveler tips, and other tourist information, read Castiglione di Sicilia route site.

You can drive from Taormina to Castiglione di Sicilia in an hour. Finish your sightseeing early on the 7th (Mon) to allow enough time to drive to Messina.

Things to do in Castiglione di Sicilia

Parks · Outdoors · Nature · Trails

Side Trips

Find places to stay Nov 5 — 7:
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Messina

— 2 nights
Messina is the capital of the Italian Metropolitan City of Messina. On the 7th (Mon), don't miss a visit to Bell Tower and Astronomical Clock (Orologio Astronomico), take in the architecture and atmosphere at Duomo di Messina, and then admire the local landmark of Fontana di Orione. Get ready for a full day of sightseeing on the next day: explore the world behind art at Museo diocesano, then get to know the fascinating history of Lungomare Falcomata, and then get engrossed in the history at Museo Archeologico Nazionale di Reggio Calabria.

For maps, traveler tips, reviews, and tourist information, use the Messina route planner.

Traveling by car from Castiglione di Sicilia to Messina takes 1.5 hours. Expect a daytime high around 67°F in November, and nighttime lows around 58°F. Wrap up your sightseeing on the 9th (Wed) early enough to travel to Lipari.

Things to do in Messina

Historic Sites · Museums

Side Trip

Find places to stay Nov 7 — 9:
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Lipari

— 2 nights
Lipari is the largest of the Aeolian Islands in the Tyrrhenian Sea off the northern coast of Sicily, southern Italy; it is also the name of the island's main town and comune, which is administratively part of the Metropolitan City of Messina. On the 9th (Wed), contemplate in the serene atmosphere at Cattedrale di San Bartolomeo, then examine the collection at Museo Archeologico Regionale Eoliano, and then tour the pleasant surroundings at Coral Beach. Keep things going the next day: make a trip to EX Cave Pomice, then pause for some serene contemplation at Chiesa Vecchia di Quattropani, and then do a tasting at Tenuta Di Castellaro.

To find ratings, photos, traveler tips, and other tourist information, you can read our Lipari trip planner.

Traveling by combination of bus and ferry from Messina to Lipari takes 3 hours. Alternatively, you can do a combination of train and ferry. In November, plan for daily highs up to 67°F, and evening lows to 58°F. Finish your sightseeing early on the 11th (Fri) so you can travel to Cefalu.

Things to do in Lipari

Historic Sites · Parks · Outdoors · Museums
Find places to stay Nov 9 — 11:
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Cefalu

— 2 nights
Cefalù is a city and comune in the Province of Palermo, located on the northern coast of Sicily, Italy on the Tyrrhenian Sea about 70km east of the provincial capital and 185km west of Messina. On the 11th (Fri), wander the streets of Cefalu Coast, take in the awesome beauty at Rocca di Cefalu, and then explore the world behind art at Museo Mandralisca. Keep things going the next day: pause for some serene contemplation at Duomo di Cefalu, stop by Enoteca le Petit Tonneau, and then don't miss a visit to Lavatoio Medievale.

To find traveler tips, reviews, where to stay, and tourist information, you can read our Cefalu visit planning site.

You can do a combination of ferry and train from Lipari to Cefalu in 4.5 hours. You'll set off for home on the 13th (Sun).

Things to do in Cefalu

Parks · Nature · Shopping · Neighborhoods
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Sicily travel guide

4.5
The largest island in the Mediterranean Sea, Sicily is a ruggedly attractive land. The island has a long history of foreign domination and has been controlled by the Greeks, Romans, Arabs, and Normans. The result is a distinct culture blending elements from all of those areas and featuring an intriguing dialect. This is a huge island with plenty of small villages to tour, each with its own treasures. Beyond the popular coastal areas, Sicily's inland attractions include an unspoiled landscape of mountains, hills, and villages that sometimes seem frozen in time. While the natural environment is its biggest draw, Sicily's greatest asset may be its people. They are proud of their traditions and incredibly hospitable to visitors.

Province of Messina travel guide

3.9
Ruins · Landmarks · Islands
Messina is the capital of the Italian Metropolitan City of Messina. It is the third-largest city on the island of Sicily, and the 13th-largest city in Italy, with a population of more than 238,000 inhabitants in the city proper and about 650,000 in the Metropolitan City. It is located near the northeast corner of Sicily, at the Strait of Messina, opposite Villa San Giovanni on the mainland, and has close ties with Reggio Calabria. According to Eurostat the FUA of the metropolitan area of Messina has, in 2014, 277,584 inhabitants.The city's main resources are its seaports (commercial and military shipyards), cruise tourism, commerce, and agriculture (wine production and cultivating lemons, oranges, mandarin oranges, and olives). The city has been a Roman Catholic Archdiocese and Archimandrite seat since 1548 and is home to a locally important international fair. The city has the University of Messina, founded in 1548 by Ignatius of Loyola.Messina has a light rail system, Tranvia di Messina, that was opened on 3 April 2003. This line is and links the city's central railway station with the city centre and harbour.

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