45 days in United States, Central America, South America & Mexico Itinerary

Make it your trip
Fly
1
Honolulu, United States
— 2 nights
Fly
2
Los Angeles, United States
— 1 night
Fly
3
Panama City, Panama
— 1 night
Fly
4
Bogota, Colombia
— 2 nights
Fly
5
Cusco, Peru
— 2 nights
Drive
6
Machu Picchu, Peru
— 4 nights
Drive
7
Cusco, Peru
— 2 nights
Fly
8
Arequipa, Peru
— 2 nights
Drive
9
Cabanaconde, Peru
— 2 nights
Drive
10
Arequipa, Peru
— 2 nights
Fly
11
Lima, Peru
— 1 night
Drive
12
Paracas, Peru
— 1 night
Drive
13
Lima, Peru
— 1 night
Fly
14
Santa Marta, Colombia
— 2 nights
Drive
15
Tayrona National Park, Colombia
— 1 night
Drive
16
Santa Marta, Colombia
— 2 nights
Drive
17
Minca, Colombia
— 2 nights
Drive
18
Santa Marta, Colombia
— 1 night
Drive to Ernesto Cortissoz International Airport, Fly to Cancun
19
Cancun, Mexico
Drive
20
Tulum, Mexico
— 10 nights
Drive
21
Cancun, Mexico
Fly
22
Mexico City, Mexico
— 2 nights

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Honolulu, United States — 2 nights

Big Pineapple

In many ways much more Asian than American, Honolulu is Hawaii's largest city and its center of government, transportation, commerce, and tourism.
Get ready for a full day of sightseeing on the 28th (Mon): kick back and relax at Waikiki Beach.

To see other places to visit, where to stay, photos, and more tourist information, use the Honolulu online itinerary planner.

Melbourne, Australia to Honolulu is an approximately 13.5-hour flight. Due to the time zone difference, you'll gain 20 hours traveling from Melbourne to Honolulu. While traveling from Melbourne, expect a bit warmer days and much hotter nights in Honolulu, ranging from highs of 34°C to lows of 26°C. On the 29th (Tue), wrap the sightseeing up by early afternoon so you can fly to Los Angeles.
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Parks · Beaches · Outdoors
Find places to stay Nov 27 — 29:
Highlights from your trip

Los Angeles, United States — 1 night

City of Angels

Surrounded by mountain ranges, forests, valleys, beaches, and deserts, the metropolitan area of Los Angeles is home to over 17 million people.
For ratings, reviews, more things to do, and tourist information, you can read our Los Angeles day trip tool.

You can fly from Honolulu to Los Angeles in 7 hours. The time zone difference moving from Hawaii-Aleutian Standard Time (HST) to Pacific Standard Time (PST) is 2 hours. Expect slightly colder temperatures when traveling from Honolulu in November; daily highs in Los Angeles reach 28°C and lows reach 15°C. On the 30th (Wed), you're off to Panama City.
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Outdoors · Parks · Tours · Nightlife
Find places to stay Nov 29 — 30:

Panama City, Panama — 1 night

Dubai of Latin America

Arguably the most modern of Central American cities, Panama City boasts a shimmering skyline of glass skyscrapers.
For photos, where to stay, maps, and other tourist information, read our Panama City tour itinerary planner.

Traveling by flight from Los Angeles to Panama City takes 10 hours. Alternatively, you can drive. Traveling from Los Angeles to Panama City, you'll lose 3 hours due to the time zone difference. Traveling from Los Angeles in November, you will find days in Panama City are somewhat warmer (35°C), and nights are much hotter (28°C). On the 1st (Thu), you're off to Bogota.
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Tours · Outdoors · Wildlife · Parks
Find places to stay Nov 30 — Dec 1:

Bogota, Colombia — 2 nights

Athens of South America

Colombia's heart and soul, Bogota has earned the nickname "Athens of South America" thanks to its abundance of universities, libraries, and lower-level schools.
To see more things to do, traveler tips, ratings, and tourist information, read our Bogota trip itinerary builder tool.

Fly from Panama City to Bogota in 5 hours. Prepare for cooler weather when traveling from Panama City in December: high temperatures in Bogota hover around 22°C and lows are around 9°C. You will have some time to spend on the 3rd (Sat) before leaving for Cusco.
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Tours · Outdoors · Nightlife · Parks
Find places to stay Dec 1 — 3:

Cusco, Peru — 2 nights

Imperial City

Capital of the Inca Empire for three centuries, World Heritage-listed Cusco is now a major tourist destination, drawing nearly 2 million annual tourists with its well-preserved colonial architecture and proximity to Machu Picchu.
To find where to stay, reviews, other places to visit, and more tourist information, go to the Cusco journey site.

Fly from Bogota to Cusco in 6.5 hours. Alternatively, you can drive; or take a bus. In December, plan for daily highs up to 24°C, and evening lows to 9°C. You'll have a few hours on the 6th (Tue) to wrap things up before traveling to Machu Picchu.
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Find places to stay Dec 3 — 6:

Machu Picchu, Peru — 4 nights

A symbol of the Incan civilization, the abandoned city of Machu Picchu represents a must-see on a Peru vacation.
To see more things to do, ratings, reviews, and tourist information, use the Machu Picchu planner.

Traveling by car from Cusco to Machu Picchu takes 4.5 hours. Alternatively, you can do a combination of bus and train; or take a train. Finish your sightseeing early on the 10th (Sat) so you can drive to Cusco.
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Historic Sites · Parks · Tours · Spas
Find places to stay Dec 6 — 10:

Cusco, Peru — 2 nights

Imperial City

For more things to do, photos, reviews, and tourist information, read our Cusco trip itinerary app.

Traveling by car from Machu Picchu to Cusco takes 4.5 hours. Alternatively, you can do a combination of train and bus; or take a train. You will have some time to spend on the 12th (Mon) before leaving for Arequipa.
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Find places to stay Dec 10 — 12:

Arequipa, Peru — 2 nights

White City

In an area dominated three imposing volcanoes, Arequipa vacations allow visitors to admire well-preserved colonial architecture in a dramatic setting.
For where to stay, other places to visit, more things to do, and more tourist information, you can read our Arequipa road trip tool.

Fly from Cusco to Arequipa in 3.5 hours. Alternatively, you can drive; or take a bus. In December, daytime highs in Arequipa are 24°C, while nighttime lows are 12°C. On the 14th (Wed), you'll have the morning to explore before heading off to Cabanaconde.
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Tours · Outdoors · Museums · Parks
Find places to stay Dec 12 — 14:

Cabanaconde, Peru — 2 nights

A vacation in Cabanaconde provides visitors with an opportunity to explore the left bank of the Colca River, an area quite untouched by commercial tourism.
Cabanaconde is known for sightseeing, nature, and parks. Your trip includes some of its best attractions: tour the pleasant surroundings at Condor's Cross and get great views at Mirador Cruz del Condor.

For traveler tips, other places to visit, photos, and other tourist information, read our Cabanaconde travel planner.

Getting from Arequipa to Cabanaconde by car takes about 4.5 hours. Other options: do a combination of bus and taxi. Finish your sightseeing early on the 16th (Fri) so you can drive to Arequipa.
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Nature · Parks · Wildlife
Find places to stay Dec 14 — 16:

Arequipa, Peru — 2 nights

White City

To find ratings, reviews, and other tourist information, use the Arequipa day trip planning app.

Drive from Cabanaconde to Arequipa in 4.5 hours. Alternatively, you can do a combination of taxi and bus. You'll have a few hours on the 18th (Sun) to wrap things up before traveling to Lima.
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Tours · Outdoors · Museums · Parks
Find places to stay Dec 16 — 18:

Lima, Peru — 1 night

City of the Kings

Founded in 1535 by Spanish explorer Francisco Pizarro, Lima represents an interesting blend of modern attractions and preserved colonial architecture, much of it clustered in the World Heritage-listed city center.
For where to stay, more things to do, maps, and more tourist information, refer to the Lima online day trip planner.

Getting from Arequipa to Lima by flight takes about 3.5 hours. Other options: drive; or take a bus. Plan for a bit warmer temperatures traveling from Arequipa in December, with highs in Lima at 28°C and lows at 22°C. You'll have a few hours on the 19th (Mon) to wrap things up before traveling to Paracas.
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Find places to stay Dec 18 — 19:

Paracas, Peru — 1 night

A port town largely devoted to tourism, Paracas serves as a popular starting point for exploration of Peru's south coast.
Start off your visit on the 19th (Mon): enjoy the sand and surf at Playa de la Mina and then step off the mainland to explore Islas Ballestas. On the 20th (Tue), you'll have a packed day of sightseeing: make a trip to The Chandelier, then see Off-Road Tours, then browse the exhibits of Pukasoncco, Arte Precolombino., and finally glide through the air with a parasailing or paragliding tour.

To see maps, ratings, photos, and other tourist information, you can read our Paracas trip planner.

Traveling by car from Lima to Paracas takes 3.5 hours. Alternatively, you can take a bus. Expect a daytime high around 28°C in December, and nighttime lows around 20°C. Cap off your sightseeing on the 20th (Tue) early enough to go by car to Lima.
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Parks · Outdoors · Tours · Nature
Find places to stay Dec 19 — 20:

Lima, Peru — 1 night

City of the Kings

To see other places to visit, maps, reviews, and tourist information, refer to the Lima trip planner.

Traveling by car from Paracas to Lima takes 3.5 hours. Alternatively, you can take a bus. You'll have a few hours on the 21st (Wed) to wrap things up before traveling to Santa Marta.
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Find places to stay Dec 20 — 21:

Santa Marta, Colombia — 2 nights

America's Pearl

Many visitors begin their Santa Marta holiday, surrounded by urban clutter and heavy traffic, expecting little from the city in terms of historical importance.
Start your trip to Santa Marta by creating a personalized itinerary on Inspirock.

Traveling by flight from Lima to Santa Marta takes 9 hours. Alternatively, you can drive; or take a bus. Traveling from Lima in December, things will get a bit warmer in Santa Marta: highs are around 39°C and lows about 28°C. Finish your sightseeing early on the 23rd (Fri) so you can drive to Tayrona National Park.
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Tours · Outdoors · Wildlife · Parks
Side Trip
Find places to stay Dec 21 — 23:

Tayrona National Park, Colombia — 1 night

On the 23rd (Fri), explore the wealth of natural beauty at Parque Nacional Natural Tayrona.

For more things to do, other places to visit, photos, and tourist information, read our Tayrona National Park trip itinerary planning tool.

You can drive from Santa Marta to Tayrona National Park in 1.5 hours. In December, plan for daily highs up to 39°C, and evening lows to 28°C. You will leave for Santa Marta on the 24th (Sat).
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Nature · Parks
Find places to stay Dec 23 — 24:
Highlights from your trip

Santa Marta, Colombia — 2 nights

America's Pearl

Kick off your visit on the 24th (Sat): take in the waterfront activity at Marina Santa Marta and then walk around Plaza Parque Simon Bolivar. Get ready for a full day of sightseeing on the 25th (Sun): look for all kinds of wild species at Wildlife Areas.

For maps, photos, and more tourist information, go to the Santa Marta trip itinerary planning website.

Getting from Tayrona National Park to Santa Marta by car takes about 1.5 hours. Finish your sightseeing early on the 26th (Mon) to allow enough time to drive to Minca.
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Outdoors · Tours · Wildlife · Parks
Find places to stay Dec 24 — 26:

Minca, Colombia — 2 nights

A Minca vacation takes you to a small mountain village nestled above Santa Marta in the Sierra Nevada.
Get ready for a full day of sightseeing on the next day: take in the dramatic scenery at Cascadas de Marinka, then see the interesting displays at Museo Minca - Memorial Museum Of The Sierra Nevada, and then get outside with Pozo Azul.

To see other places to visit, more things to do, traveler tips, and tourist information, refer to the Minca journey planning site.

Traveling by car from Santa Marta to Minca takes an hour. Alternatively, you can take a bus. In December in Minca, expect temperatures between 39°C during the day and 28°C at night. On the 28th (Wed), wrap the sightseeing up by early afternoon so you can drive to Santa Marta.
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Nature · Parks · Outdoors · Spas
Find places to stay Dec 26 — 28:

Santa Marta, Colombia — 1 night

America's Pearl

On the 28th (Wed), contemplate the long history of Alcaldia de Santa Marta, then take in nature's colorful creations at Quinta de San Pedro Alejandrino, and then pause for some photo ops at Monumento Tayrona.

To find traveler tips, ratings, more things to do, and tourist information, you can read our Santa Marta online vacation maker.

You can drive from Minca to Santa Marta in an hour. Another option is to take a bus. Finish your sightseeing early on the 29th (Thu) to allow enough time to travel to Cancun.
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Parks · Museums · Historic Sites
Find places to stay Dec 28 — 29:

Cancun, Mexico

Few destinations in Mexico dazzle visitors quite like Cancun, a modern resort town filled with glitzy hotels sitting on picturesque and well-developed Caribbean beaches.
To see maps, reviews, more things to do, and more tourist information, read our Cancun trip itinerary planner.

The Route module can help you plan travel from Santa Marta to Cancun. In December, Cancun is a bit cooler than Santa Marta - with highs of 32°C and lows of 24°C. You will leave for Tulum on the 29th (Thu).
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Find places to stay Dec 29 — 30:

Tulum, Mexico — 10 nights

The only Mayan site built to overlook the ocean, Tulum remains a coastal paradise preserving the last vestiges of a pre-Hispanic civilization.
Explore Tulum's surroundings by going to Zona Arqueologica de Coba (in Coba) and Chichen Itza (in Chichen Itza). There's lots more to do: enjoy the sand and surf at Paradise Beach, contemplate the waterfront views at Casa Cenote, Head underground at Cenotes Sac Actun, and stroll through LabnaHa Cenotes & Eco Park.

To see maps, more things to do, other places to visit, and other tourist information, read our Tulum vacation planner.

Drive from Cancun to Tulum in 2 hours. Alternatively, you can take a shuttle; or take a bus. In December, plan for daily highs up to 31°C, and evening lows to 23°C. Cap off your sightseeing on the 8th (Sun) early enough to go by car to Cancun.
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Parks · Beaches · Outdoors · Historic Sites
Side Trips
Find places to stay Dec 29 — Jan 8:

Cancun, Mexico

To find maps, more things to do, photos, and more tourist information, read Cancun itinerary planner.

You can drive from Tulum to Cancun in 2 hours. Alternatively, you can take a shuttle; or take a bus. You will leave for Mexico City on the 8th (Sun).
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Find places to stay Jan 8 — 9:

Mexico City, Mexico — 2 nights

City of Palaces

Breathtakingly large, Mexico City provides a home for almost 9 million people living in nearly 1,700 distinct neighborhoods.
Start off your visit on the 9th (Mon): pause for some serene contemplation at Basilica de Santa Maria de Guadalupe, then admire the landmark architecture of Metropolitan Cathedral (Catedral Metropolitana), then get to know the fascinating history of Zocalo, and finally take in the exciting artwork at Yawi Arte Tradicional. On the 10th (Tue), you'll have a packed day of sightseeing: make a trip to Museo Frida Kahlo, then learn more about the world around you at Museo Nacional de Antropologia, and then look for gifts at MAM Boutique.

To find photos, traveler tips, reviews, and more tourist information, read our Mexico City trip maker website.

Fly from Cancun to Mexico City in 4 hours. Alternatively, you can drive; or take a bus. You'll gain 1 hour traveling from Cancun to Mexico City due to the time zone difference. Expect slightly colder weather when traveling from Cancun in January: highs in Mexico City hover around 24°C, while lows dip to 7°C. Finish your sightseeing early on the 10th (Tue) so you can travel back home.
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Find places to stay Jan 8 — 10:

United States travel guide

4.6
More than the country of car-packed streets seen in TV shows and movies, the United States of America is a complex and diverse home to over 300 million people living in a wide range of landscapes and climates. From its big-city skyscrapers to its sprawling natural parks, the country's ''melting pot'' combines many ethnic groups that share a strong sense of national identity despite their cultural differences. A country of road trips and big blue skies, the United States harbors orderly cities filled with restaurants, parks, museums, and innumerable sightseeing opportunities, as well as pristine natural areas perfect for a holiday in the great outdoors. To see as much as you can of this diverse land quickly, drive over some of the more than 6 million km (4 million mi) of highways leading through deserts, mountain peaks, fertile fields, and giant urban centers.
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Colca Canyon travel guide

4
Hot Springs · Landmarks · Lookouts
Take a trip to Colca Canyon, the world's second deepest canyon, and witness its diverse landscapes, rich culture, and varied wildlife. With a long history of inhabitation, the Colca Valley features pre-Incan archaeological sites and ruins, stepped Incan terraces, and rustic colonial-era settlements. Roam among vicunas and cacti plants, see condors flying in close range, and witness the plunging canyon, in some places as deep as 3,300 m (11,000 ft). During your Colca Canyon vacation you can also visit Spanish settlements, relatively unchanged since colonial times, relax in the area's numerous hot springs, and purchase colorful arts and crafts made by the native Cabana and Collagua people.
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Mexico travel guide

4.5
Tailor-made for anyone seeking that traditional sun-and-sand experience, Mexico vacations allow visitors to explore nearly 10,000 km (6,200 mi) of picturesque coastlines. Idyllic beaches and favorable year-round weather aside, this diverse country with a rich pre-Colombian history allows tourists a chance to discover a fascinating cuisine, numerous archaeological sites, state-of-the-art museums, colonial-era haciendas, and outstanding examples of 21st-century architecture. Most visitors get to know the country by its cities, but if you want a well-rounded Mexico tour, spend some time exploring its jungles, cloud forests, Caribbean reefs, snowcapped volcanoes, vast deserts, and tranquil lagoons. Life is lived outdoors in Mexico, so wherever you go, don't forget to dine alfresco and stroll the country's colonial streets.
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