45 days in South America Itinerary

45 days in South America Itinerary

Created using Inspirock South America travel route planner

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Route & dates

45 days in South America Itinerary

Start: Manchester, United Kingdom
Fly:  17​h 30​min
1
Fernando de Noronha, Brazil
— 4 nights
+2
Fly + bus + taxi:  9​h
2
Ouro Preto, Brazil
— 1 night
Drive:  5​h 15​min
3
Rio de Janeiro, Brazil
— 3 nights
4
Bonito, Brazil
— 3 nights
+3
Fly + bus + foot + bus:  12​h 30​min
5
Urubici, Brazil
— 2 nights
6
Gramado, Brazil
— 2 nights
bus + Fly:  9​h 30​min
7
Ushuaia, Argentina
— 3 nights
Fly:  7​h 30​min
8
San Carlos de Bariloche, Argentina
— 3 nights
Fly:  6​h 45​min
9
Salta, Argentina
— 2 nights
Drive:  8​h 15​min
10
San Pedro de Atacama, Chile
— 3 nights
shuttle + Fly:  8​h 15​min
11
Cusco, Peru
— 3 nights
+2
Fly + shuttle + ferry:  16​h
12
Puerto Ayora, Ecuador
— 3 nights
+2
Drive + Fly + Drive:  19​h 30​min
13
Alto Paraiso de Goias, Brazil
— 4 nights
Drive + Fly:  19​h 30​min
End: Manchester, United Kingdom

4
nights
Fernando de Noronha, Brazil

Fernando de Noronha ©
With 21 lush islands scattered among pristine waters in the Atlantic Ocean, a Fernando de Noronha holiday is well worth the effort it takes to get there.
You'll discover tucked-away gems like Baia dos Porcos and Fernando de Noronha. There's still lots to do: tour the pleasant surroundings at Praia do Cachorro, enjoy breathtaking views from Forte Sao Pedro do Boldro, enjoy the sand and surf at Praia do Leão, and see the interesting displays at Projeto TAMAR Fernando de Noronha - Patrocínio PETROBRAS.

To see traveler tips, photos, ratings, and tourist information, go to the Fernando de Noronha trip planner .

Manchester, UK to Fernando de Noronha is an approximately 17.5-hour flight. You can also do a combination of train and flight; or do a combination of bus and flight. The time zone changes from Greenwich Mean Time (GMT) to Fernando de Noronha Time (FNT), which is usually a -2 hour difference. Expect a bit warmer weather when traveling from Manchester in July: highs in Fernando de Noronha hover around 33°C, while lows dip to 28°C. Finish your sightseeing early on the 30th (Thu) so you can travel to Ouro Preto.

Things to do in Fernando de Noronha

Outdoors Parks Beaches
Find places to stay Jul 26 — 30:
Highlights from your plan
Baia dos Porcos ©
Baia dos Porcos
Praia do Cacimba do Padre ©
Praia do Cacimba do Padre
Conceicao Beach ©
Conceicao Beach

1
night
Ouro Preto, Brazil

Ouro Preto ©
Designated a World Heritage Site because of its well-preserved Baroque architecture, the city of Ouro Preto served as the state capital until local governance outgrew the scale of this pleasant valley settlement.
Start off your visit on the 31st (Fri): admire the striking features of Basilica of Nossa Senhora do Pilar, explore the world behind art at Museu da Inconfidencia, then take in the architecture and atmosphere at Church of Sao Francisco de Assis, and finally get engrossed in the history at Casa dos Contos. Get ready for a full day of sightseeing on the 1st (Sat): go deep underground at Minas da Passagem, make a trip to Praca Tiradentes, then admire the landmark architecture of Igreja Nossa Senhora do Carmo, and finally examine the collection at Museum of Mineralogy.

Plan my Ouro Preto trip by asking Inpirock to come up with tips and suggestions.

Getting from Fernando de Noronha to Ouro Preto by combination of flight, bus, and taxi takes about 9 hours. Other options: do a combination of flight, train, and taxi. The time zone changes from Fernando de Noronha Time to Brasilia Time, which is usually a -1 hour difference. Traveling from Fernando de Noronha in July, expect a bit cooler with lows of 20°C in Ouro Preto. Wrap up your sightseeing on the 1st (Sat) early enough to drive to Rio de Janeiro.

Things to do in Ouro Preto

Museums Historic Sites

Side Trip

Minas da Passagem
Find places to stay Jul 30 — Aug 1:
Highlights from your plan
Museu da Inconfidencia ©
Museu da Inconfidencia
Basilica of Nossa Senhora do Pilar ©
Basilica of Nossa Senhora do Pilar
Casa dos Contos ©
Casa dos Contos

3
nights
Rio de Janeiro, Brazil

Rio de Janeiro ©
Bustling with samba music and all-night street parties, no city encapsulates the spirit of Brazil better than Rio de Janeiro.
Rio de Janeiro is known for beaches, nature, parks, museums, and nightlife. Your plan includes some of its best attractions: take your sightseeing to a higher altitude at Pao de Acucar, kick back and relax at Copacabana Beach, make a trip to Escadaria Selaron, and tour the pleasant surroundings at Praia de Ipanema.

To see more things to do, maps, reviews, and more tourist information, go to the Rio de Janeiro journey maker .

Traveling by car from Ouro Preto to Rio de Janeiro takes 5.5 hours. Alternatively, you can do a combination of taxi and bus; or take a bus. In August, daily temperatures in Rio de Janeiro can reach 30°C, while at night they dip to 22°C. Wrap up your sightseeing on the 4th (Tue) early enough to travel to Bonito.

Things to do in Rio de Janeiro

Parks Nature Beaches
Find places to stay Aug 1 — 4:
Highlights from your plan
Corcovado Christ the Redeemer ©
Corcovado Christ the Redeemer
Bondinho  Pao de Acucar ©
Bondinho Pao de Acucar
Copacabana Beach ©
Copacabana Beach

3
nights
Bonito, Brazil

Bonito ©
A popular hub of ecotourism, Bonito offers plenty of attractions and activities for visitors in search of an adventurous, nature-filled holiday in Brazil.
You'll explore the less-touristy side of things at Lagoa Misteriosa and Gruta Sao Mateus. Step out of Bonito with an excursion to Cachoeira Boca da Onca in Bodoquena--about 1h 25 min away. Next up on the itinerary: explore the fascinating underground world of Grutas de Sao Miguel, explore the activities along Rio Sucuri, and get up close and personal with brilliant marine life at Aquario Natural.

For maps, traveler tips, more things to do, and other tourist information, go to the Bonito trip itinerary planning site .

You can fly from Rio de Janeiro to Bonito in 4.5 hours. Alternatively, you can drive; or take a bus. The time zone changes from Brasilia Time to Amazon Time, which is usually a -1 hour difference. Cap off your sightseeing on the 7th (Fri) early enough to travel to Urubici.

Things to do in Bonito

Parks Nature Wildlife

Side Trip

Cachoeira Boca da Onca
Find places to stay Aug 4 — 7:
Highlights from your plan
Rio Sucuri ©
Rio Sucuri
Lagoa Misteriosa ©
Lagoa Misteriosa
Cachoeira Boca da Onca ©
Cachoeira Boca da Onca

2
nights
Urubici, Brazil

Urubici ©
With average temperatures ranging between 12 C (54 F) and 16 C (61 F), and the possibility of snow in winter, Urubici is officially the coldest town in Brazil.
Step off the beaten path and head to Morro da Igreja and Gruta Nossa Senhora de Lourdes. Take a break from Urubici with a short trip to Serra do Corvo Branco in Grao Para, about 40 minutes away. There's much more to do: take in the dramatic scenery at Cachoeira do Avencal, take in the awesome beauty at Morro do Campestre, and take in the architecture and atmosphere at Igreja Matriz Nossa Senhora Mae dos Homens.

To find reviews, more things to do, and other tourist information, read Urubici tour itinerary maker tool .

Do a combination of flight and bus from Bonito to Urubici in 12.5 hours. Alternatively, you can drive; or do a combination of flight and car. Wrap up your sightseeing on the 10th (Mon) early enough to drive to Gramado.

Things to do in Urubici

Parks Nature Historic Sites

Side Trip

Serra do Corvo Branco
Find places to stay Aug 8 — 10:
Highlights from your plan
Cachoeira do Avencal ©
Cachoeira do Avencal
Morro da Igreja ©
Morro da Igreja
Serra do Corvo Branco ©
Serra do Corvo Branco

2
nights
Gramado, Brazil

Gramado ©
Surrounded by impressive mountain scenery in the state of Rio Grande do Sul, the small city of Gramado charms visitors with its alpine European-style architecture and blossoming flowers.
Eschew the tourist crowds and head to Parque da Ferradura and Praca das Etnias. When in Gramado, make a side trip to see Labirinto Verde in Nova Petropolis, approximately 42 minutes away. There's still lots to do: admire the sheer force of Cascata do Caracol, pause for some photo ops at Praca Major Nicoletti, stroll around Mini Mundo, and steep yourself in history at Casa do Colono.

To see more things to do, where to stay, reviews, and tourist information, read our Gramado tour itinerary builder tool .

You can drive from Urubici to Gramado in 6 hours. Another option is to take a bus. The time zone changes from Amazon Time (AMT) to Brasilia Time (BRT), which is usually a 1 hour difference. Wrap up your sightseeing on the 13th (Thu) early enough to travel to Ushuaia.

Things to do in Gramado

Parks Wildlife Zoos & Aquariums

Side Trips

Canela, Labirinto Verde
Find places to stay Aug 10 — 13:
Highlights from your plan
Parque da Ferradura ©
Parque da Ferradura
Casa do Colono ©
Casa do Colono
Labirinto Verde ©
Labirinto Verde

3
nights
Ushuaia, Argentina

Ushuaia ©
Often called the "End of the World" because of its position on the southernmost tip of South America, the expanding city of Ushuaia serves as both a busy commercial port and attractive tourist hub.
You'll discover tucked-away gems like Cerro Castor (Castor Mount) and Mirador de Lagos Escondido y Fagnano. And it doesn't end there: take an unforgettable tour with a helicopter tour, explore the activities along Bahia Lapataia, pause for some photo ops at Plaza Malvinas, and tour the pleasant surroundings at Glacier Martial.

For traveler tips, maps, ratings, and tourist information, read Ushuaia trip maker site .

You can do a combination of bus and flight from Gramado to Ushuaia in 9.5 hours. Alternatively, you can do a combination of car and ferry; or take a bus. Expect a daytime high around 5°C in August, and nighttime lows around 0°C. Cap off your sightseeing on the 17th (Mon) early enough to travel to San Carlos de Bariloche.

Things to do in Ushuaia

Parks Nature Outdoors
Find places to stay Aug 13 — 17:
Highlights from your plan
Cerro Castor (Castor Mount) ©
Cerro Castor (Castor Mount)
Les Éclaireurs Lighthouse ©
Les Éclaireurs Lighthouse
Helicopter Tours

3
nights
San Carlos de Bariloche, Argentina

San Carlos de Bariloche ©
Nestled against the foothills of the Andes, scenic San Carlos de Bariloche hugs the southern shore of Nahuel Huapi Lake and ranks among Argentina's top destinations for active outdoor vacations.
You'll explore the less-touristy side of things at Piedras Blancas and Parroquia San Eduardo. There's lots more to do: stroll around Parque Nahuelito, examine the collection at Museo del Lago Gutierrez, head off the coast to Isla Victoria, and contemplate the geological forces at Cerro Tronador.

To see other places to visit, photos, reviews, and tourist information, read our San Carlos de Bariloche holiday planner.

Traveling by flight from Ushuaia to San Carlos de Bariloche takes 7.5 hours. Alternatively, you can do a combination of car and ferry; or take a bus. Expect somewhat warmer weather when traveling from Ushuaia in August: highs in San Carlos de Bariloche hover around 9°C, while lows dip to 0°C. Wrap up your sightseeing on the 21st (Fri) to allow time to travel to Salta.

Things to do in San Carlos de Bariloche

Parks Outdoors Nature
Find places to stay Aug 17 — 21:
Highlights from your plan
Ventisquero Negro ©
Ventisquero Negro
Parque Nacional Nahuel Huapi ©
Parque Nacional Nahuel Huapi
Isla Victoria ©
Isla Victoria

2
nights
Salta, Argentina

Salta ©
Salta boasts a vibrant social life and array of informative museums appealing to visitors looking for a memorable cultural experience.
Start off your visit on the 22nd (Sat): take your sightseeing to a higher altitude at Cuesta del Obispo and then take in the spiritual surroundings of Cathedral of Salta. Get ready for a full day of sightseeing on the 23rd (Sun): take in the awesome beauty at Cerro San Bernardo and then take in the dramatic natural features at El Anfiteatro (The Amphitheatre).

To see traveler tips, ratings, more things to do, and tourist information, refer to the Salta online trip itinerary planner .

Fly from San Carlos de Bariloche to Salta in 7 hours. Alternatively, you can do a combination of flight, taxi, and bus; or drive. Traveling from San Carlos de Bariloche in August, you will find days in Salta are warmer (27°C), and nights are somewhat warmer (5°C). Wrap up your sightseeing on the 23rd (Sun) early enough to drive to San Pedro de Atacama.

Things to do in Salta

Parks Nature Historic Sites
Find places to stay Aug 21 — 23:
Highlights from your plan
Cuesta del Obispo ©
Cuesta del Obispo
Cathedral of Salta ©
Cathedral of Salta
Cerro San Bernardo ©
Cerro San Bernardo

3
nights
San Pedro de Atacama, Chile

San Pedro de Atacama ©
Major archeological sites and a renowned museum remain the big draws in San Pedro de Atacama tourism, appealing to visitors interested in learning more about South America's pre-Columbian cultures.
Discover out-of-the-way places like Tebinquinche Lake and Piedras Rojas. Spend the 27th (Thu) exploring nature at Reserva Nacional de Flamencos. There's lots more to do: look for all kinds of wild species at Salar de Tara, get curious at Museo del Meteorito, take in the natural beauty of Termas Banos de Puritama, and don't miss a visit to Mirador de Kari, Piedra del Coyote.

For photos, ratings, and other tourist information, go to the San Pedro de Atacama visit planning app .

Traveling by car from Salta to San Pedro de Atacama takes 8.5 hours. Alternatively, you can take a bus. Traveling from Salta to San Pedro de Atacama, you'll gain 1 hour due to the time zone difference. Plan for slightly colder nights when traveling from Salta in August since evenings lows in San Pedro de Atacama dip to 0°C. Finish your sightseeing early on the 27th (Thu) to allow enough time to travel to Cusco.

Things to do in San Pedro de Atacama

Parks Nature Wildlife
Find places to stay Aug 23 — 27:
Highlights from your plan
Salar de Tara ©
Salar de Tara
Tebinquinche Lake ©
Tebinquinche Lake
Piedras Rojas ©
Piedras Rojas

3
nights
Cusco, Peru

Cusco ©
Capital of the Inca Empire for three centuries, World Heritage-listed Cusco is now a major tourist destination, drawing nearly 2 million annual tourists with its well-preserved colonial architecture and proximity to Machu Picchu.
Step off the beaten path and head to Sacred Valley of the Incas and Q'enqo. Change things up with a short trip to Pisac in Pisac (about 52 minutes away). And it doesn't end there: delve into the distant past at Sacsayhuaman, steep yourself in history at Tipon, indulge in some personalized pampering at some of the best spas, and take a stroll through San Blas.

To see maps, other places to visit, traveler tips, and tourist information, read Cusco road trip website .

Traveling by combination of shuttle and flight from San Pedro de Atacama to Cusco takes 8.5 hours. Alternatively, you can drive; or take a bus. The time zone difference when traveling from San Pedro de Atacama to Cusco is minus 1 hour. In August, daily temperatures in Cusco can reach 24°C, while at night they dip to 2°C. Finish your sightseeing early on the 30th (Sun) so you can travel to Puerto Ayora.

Things to do in Cusco

Historic Sites Spas Neighborhoods

Side Trips

Sacred Valley of the Incas, Pisac
Find places to stay Aug 27 — 30:
Highlights from your plan
Sacsayhuaman ©
Sacsayhuaman
Pisac ©
Pisac
Sacred Valley of the Incas ©
Sacred Valley of the Incas

3
nights
Puerto Ayora, Ecuador

Puerto Ayora ©
The largest settlement in the Galapagos, Puerto Ayora offers visitors to the islands an array of facilities and things to do.
Discover out-of-the-way places like El Chato - Giant Tortoise Reserve and Las Grietas. There's still lots to do: enjoy the sand and surf at El Garrapatero, look for all kinds of wild species at Charles Darwin Research Station, don't miss a visit to Santa Cruz Fish Market, and tour the pleasant surroundings at Galapagos Beach at Tortuga Bay.

For maps, more things to do, and more tourist information, use the Puerto Ayora journey maker tool .

Do a combination of flight and ferry from Cusco to Puerto Ayora in 16 hours. While traveling from Cusco, expect a bit warmer days and much hotter nights in Puerto Ayora, ranging from highs of 30°C to lows of 24°C. Finish your sightseeing early on the 3rd (Thu) so you can travel to Alto Paraiso de Goias.

Things to do in Puerto Ayora

Parks Beaches Wildlife

Side Trip

Galapagos Beach at Tortuga Bay
Find places to stay Aug 31 — Sep 3:
Highlights from your plan
Galapagos Beach at Tortuga Bay ©
Galapagos Beach at Tortuga Bay
El Garrapatero ©
El Garrapatero
El Chato - Giant Tortoise Reserve ©

4
nights
Alto Paraiso de Goias, Brazil

Alto Paraiso de Goias ©
Developed from a 19th-century cattle ranch, Alto Paraiso de Goias serves as the major gateway to a World Heritage-listed national park known for containing some of the world's oldest natural rock formations.
You'll discover tucked-away gems like Catarata dos Couros and Gota Kaliandra - Espaco de Musica e Silencio. The adventure continues: take in the dramatic scenery at Almecegas I Waterfalls, explore the wealth of natural beauty at Parque Nacional da Chapada dos Veadeiros, stroll around Santuario Ecologico Vale Dourado, and explore the striking landscape at Vale da Lua.

To find reviews, photos, ratings, and other tourist information, use the Alto Paraiso de Goias sightseeing site .

The Route module can help you plan travel from Puerto Ayora to Alto Paraiso de Goias. You'll lose 1 hour traveling from Puerto Ayora to Alto Paraiso de Goias due to the time zone difference. Wrap up your sightseeing by early afternoon on the 7th (Mon) to allow enough time to travel back home.

Things to do in Alto Paraiso de Goias

Parks Nature Wildlife

Side Trip

Cachoeira Santa Barbara
Find places to stay Sep 3 — 7:
Highlights from your plan
Vale da Lua ©
Vale da Lua
Almecegas I Waterfalls ©
Almecegas I Waterfalls

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