4 days in Cusco & Iquitos Itinerary

Capital of the Inca Empire for three centuries, World Heritage-listed Cusco is now a major tourist destination, drawing nearly 2 million annual tourists with its well-preserved colonial architecture and proximity to Machu Picchu.

Kick off your visit on the 15th (Tue): explore the ancient world of Qorikancha, then contemplate the long history of Sacsayhuaman, and then contemplate the long history of Plaza de Armas.

To find maps, photos, and other tourist information, you can read our Cusco vacation planner.

Los Angeles, USA to Cusco is an approximately 14-hour flight. You'll lose 3 hours traveling from Los Angeles to Cusco due to the time zone difference. Traveling from Los Angeles in June, you will find days in Cusco are a bit cooler (69°F), and nights are cooler (35°F). Finish your sightseeing early on the 15th (Tue) to allow enough time to travel to Iquitos.

The largest city in the Peruvian Amazon and the world's largest metropolis unreachable by road, Iquitos represents a major starting point for river and rainforest adventures.

Your day by day itinerary now includes La Isla De Los Monos. Kick off your visit on the 16th (Wed): see the interesting displays at Museum of Indigenous Amazonian Cultures, then stop by Centro Artesanal Turistico Anaconda, then stroll through La Isla De Los Monos, and finally examine the collection at Museum of Historic Boats.

To see photos, where to stay, and tourist information, read Iquitos trip itinerary tool.

You can fly from Cusco to Iquitos in 4 hours. Another option is to do a combination of bus, ferry, and taxi. While traveling from Cusco, expect a bit warmer days and warmer nights in Iquitos, ranging from highs of 88°F to lows of 71°F. Cap off your sightseeing on the 17th (Thu) early enough to travel back home.