39 days in Mexico, Central America & South America Itinerary

39 days in Mexico, Central America & South America Itinerary

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Route & dates

39 days in Mexico, Central America & South America Itinerary

Start: Cancun, Mexico
Drive:  1​h
1
Playa del Carmen, Mexico
— 2 nights
+2
bus + foot + ferry:  6​h 15​min
2
San Pedro, Belize
— 4 nights
Fly:  3​h 30​min
3
Guatemala City, Guatemala
— 2 nights
+3
Fly + bus + foot + shuttle:  9​h
4
San Juan del Sur, Nicaragua
— 1 night
Drive + bus:  6​h
5
San Jose, Costa Rica
— 2 nights
+2
bus + Drive + ferry:  7​h 30​min
6
Isla Bastimentos, Panama
— 2 nights
ferry + Fly:  3​h 45​min
7
Panama City, Panama
— 1 night
taxi + Fly:  2​h 15​min
8
Bogota, Colombia
— 2 nights
9
Lima, Peru
— 2 nights
Fly:  5​h 45​min
10
La Paz, Bolivia
— 2 nights
Fly:  13​h
11
Natal, Brazil
— 5 nights
Fly:  8​h 15​min
12
Florianopolis, Brazil
— 7 nights
13
Rio de Janeiro, Brazil
— 3 nights
End: Rio de Janeiro, Brazil

2
nights
Playa del Carmen, Mexico

Playa del Carmen ©
The tourist hub of the popular Mayan Riviera, upscale Playa del Carmen remains the jewel of Mexico's Caribbean coastline.
Take a break from the city and head to Yal-ku Lagoon and La Playa Xpuha. You'll find plenty of places to visit near Playa del Carmen: Ruins of Tulum (in Tulum) and Aktun Chen (in Akumal). Spend the 3rd (Tue) among aquatic life with a scuba or snorkeling tour.

To see traveler tips, more things to do, where to stay, and other tourist information, use the Playa del Carmen visit planner .

Cancun to Playa del Carmen is an approximately 1-hour car ride. You can also take a bus. Traveling from Cancun in April, expect little chillier with lows of 23°C in Playa del Carmen. Finish your sightseeing early on the 5th (Thu) to allow enough time to travel to San Pedro.

Things to do in Playa del Carmen

Outdoors Wildlife Parks

Side Trips

Akumal, La Playa Xpuha, Ruins of Tulum
Find places to stay Apr 2 — 5:
Highlights from your plan
La Playa Xpuha ©
La Playa Xpuha
Scuba & Snorkeling
Aktun Chen ©
Aktun Chen

4
nights
San Pedro, Belize

San Pedro ©
San Pedro evolved from small fishing village and now represents one of the most visited locations in Belize.
Do some cultural sightseeing at The Gallery of San Pedro and Red Flower Gallery. Get outdoors at Hol Chan Marine Reserve and The Estuary of Caye Caulker. Spend the 7th (Sat) among aquatic life with a scuba or snorkeling tour. There's still lots to do: let the river carry you with a rafting and tubing tour, view the masterpieces at Belizean Arts, soothe aching muscles at some of the top local wellness centers, and look for gifts at Belize Chocolate Company.

Discover how to plan a San Pedro trip in just a few steps with Inspirock's itinerary builder.

Traveling by combination of bus and flight from Playa del Carmen to San Pedro takes 5 hours. Alternatively, you can do a combination of bus and ferry. You'll gain 1 hour traveling from Playa del Carmen to San Pedro due to the time zone difference. Traveling from Playa del Carmen in April, plan for somewhat warmer nights in San Pedro, with lows around 28°C. Finish your sightseeing early on the 10th (Tue) to allow enough time to travel to Guatemala City.

Things to do in San Pedro

Wildlife Outdoors Parks

Side Trips

Ambergris Caye, Caye Caulker
Find places to stay Apr 5 — 10:
Highlights from your plan
Hol Chan Marine Reserve ©
Hol Chan Marine Reserve
River Rafting & Tubing
Scuba & Snorkeling

2
nights
Guatemala City, Guatemala

Guatemala City ©
The largest city in Central America and the country's capital, Guatemala City contains historic sights and modern businesses.
On the 11th (Wed), see the interesting displays at Museo del Ferrocarril, then admire the masterpieces at Museum of Modern Art Carlos Merida, then meet the residents at La Aurora Zoo, and finally wander the streets of Zona Viva. Get ready for a full day of sightseeing on the 12th (Thu): take in the spiritual surroundings of Catedral Metropolitana, admire the masterpieces at Palacio Nacional, then have fun and explore at Childrens Museum, and finally buy something for everyone on your list at La Noria.

For photos, traveler tips, where to stay, and other tourist information, read our Guatemala City trip itinerary maker app .

You can fly from San Pedro to Guatemala City in 3.5 hours. Other options are to do a combination of ferry, car, and flight; or do a combination of ferry and bus. Expect slightly colder temperatures when traveling from San Pedro in April; daily highs in Guatemala City reach 32°C and lows reach 17°C. Finish your sightseeing early on the 12th (Thu) so you can travel to San Juan del Sur.

Things to do in Guatemala City

Museums Shopping Historic Sites
Find places to stay Apr 10 — 12:
Highlights from your plan
Palacio Nacional ©
Palacio Nacional
La Aurora Zoo ©
La Aurora Zoo
Catedral Metropolitana ©
Catedral Metropolitana

1
night
San Juan del Sur, Nicaragua

San Juan del Sur ©
Set in a crescent-shaped bay, San Juan del Sur has become known as a popular surfing spot and coastal holiday destination for Nicaraguan families and international visitors alike.
On the 13th (Fri), enjoy the sand and surf at San Juan del Sur Beach and then kick back and relax at La Flor Beach Natural Reserve.

For ratings, maps, other places to visit, and more tourist information, refer to the San Juan del Sur road trip site .

You can do a combination of flight and shuttle from Guatemala City to San Juan del Sur in 9 hours. Alternatively, you can do a combination of flight, bus, and shuttle; or drive. In April, San Juan del Sur is somewhat warmer than Guatemala City - with highs of 38°C and lows of 30°C. Finish your sightseeing early on the 14th (Sat) so you can travel to San Jose.

Things to do in San Juan del Sur

Parks Outdoors Beaches
Find places to stay Apr 12 — 14:
Highlights from your plan
La Flor Beach Natural Reserve ©
La Flor Beach Natural Reserve
San Juan del Sur Beach ©
San Juan del Sur Beach

2
nights
San Jose, Costa Rica

San Jose ©
A trip to San Jose, the capital, commercial center, and cultural hub of Costa Rica, gives you a chance to experience the lively atmosphere and rich cultural past of this vibrant country.
On the 14th (Sat), identify plant and animal life at Top Travel Costa Rica and then indulge your thirst for a good beer at Costa Rica's Craft Brewing Co.. On the next day, identify plant and animal life at Toucan Rescue Ranch, take an in-depth tour of National Museum (Museo Nacional), and then take in the exciting artwork at Galeria Namu.

To find reviews, other places to visit, photos, and other tourist information, you can read our San Jose online day trip planner .

Do a combination of shuttle, flight, and taxi from San Juan del Sur to San Jose in 5 hours. Alternatively, you can drive; or do a combination of car and bus. In April, San Jose is a bit cooler than San Juan del Sur - with highs of 33°C and lows of 22°C. Finish up your sightseeing early on the 16th (Mon) so you can travel to Isla Bastimentos.

Things to do in San Jose

Wildlife Breweries Museums

Side Trip

Toucan Rescue Ranch
Find places to stay Apr 14 — 16:
Highlights from your plan
Toucan Rescue Ranch ©
Toucan Rescue Ranch
Top Travel Costa Rica ©
Top Travel Costa Rica
Galeria Namu ©
Galeria Namu

2
nights
Isla Bastimentos, Panama

Isla Bastimentos ©
Sitting fairly close to the mainland and just a short boat ride from Bocas del Toro International Airport, the well-connected but still preserved Isla Bastimentos offers access to a national park of protected rainforest and coastline, as well as an abundance of small, uninhabited islands dotted just offshore.
On the 16th (Mon), enjoy the sand and surf at Red Frog Beach.

To find traveler tips, ratings, reviews, and more tourist information, use the Isla Bastimentos trip maker website .

You can do a combination of flight and ferry from San Jose to Isla Bastimentos in 3.5 hours. Another option is to do a combination of bus, car, and ferry. You'll lose 1 hour traveling from San Jose to Isla Bastimentos due to the time zone difference. Traveling from San Jose in April, you can expect nighttime temperatures to be a bit warmer in Isla Bastimentos, with lows of 30°C. On the 18th (Wed), you're off toPanama City.

Things to do in Isla Bastimentos

Parks Outdoors Beaches
Find places to stay Apr 16 — 18:
Highlights from your plan
Red Frog Beach ©
Red Frog Beach

1
night
Panama City, Panama

Arguably the most modern of Central American cities, Panama City boasts a shimmering skyline of glass skyscrapers.
Kick off your visit on the 18th (Wed): get engrossed in the history at Museo del Canal Interoceanico de Panama and then kick back and relax at Isla Santa Catalina. Get ready for a full day of sightseeing on the next day: surround yourself with nature on a nature and wildlife tour.

For reviews, photos, more things to do, and tourist information, read Panama City vacation planning app .

Do a combination of ferry, flight, and shuttle from Isla Bastimentos to Panama City in 4 hours. Alternatively, you can do a combination of ferry, bus, and taxi; or do a combination of ferry, bus, and shuttle. Traveling from Isla Bastimentos in April, you will find days in Panama City are somewhat warmer (38°C), and nights are about the same (30°C). Finish your sightseeing early on the 19th (Thu) so you can travel to Bogota.

Things to do in Panama City

Outdoors Wildlife Tours

Side Trips

Nature & Wildlife Tours, Isla Santa Catalina
Find places to stay Apr 18 — 19:
Highlights from your plan
Nature & Wildlife Tours
Isla Santa Catalina ©
Isla Santa Catalina

2
nights
Bogota, Colombia

Bogota ©
Colombia's heart and soul, Bogota has earned the nickname "Athens of South America" thanks to its abundance of universities, libraries, and lower-level schools.
Kick off your visit on the 20th (Fri): tour the pleasant surroundings at Parque de Usaquen, then take a stroll through Parque 93, and then take in nature's colorful creations at Jardin Botanico de Bogota Jose Celestino Mutis. On your second day here, take in the awesome beauty at Mount Monserrate and then make a trip to Zona G Bogota.

To plan Bogota vacation without wasting time, ask Inspirock to design an itinerary.

You can fly from Panama City to Bogota in 2.5 hours. Prepare for colder weather when traveling from Panama City in April: high temperatures in Bogota hover around 22°C and lows are around 11°C. Finish your sightseeing early on the 21st (Sat) to allow enough time to travel to Lima.

Things to do in Bogota

Parks Neighborhoods Wildlife
Find places to stay Apr 19 — 21:
Highlights from your plan
Mount Monserrate ©
Mount Monserrate
Parque 93 ©
Parque 93

2
nights
Lima, Peru

Lima ©
Founded in 1535 by Spanish explorer Francisco Pizarro, Lima represents an interesting blend of modern attractions and preserved colonial architecture, much of it clustered in the World Heritage-listed city center.
On the 22nd (Sun), take a stroll through Barranco, then snap pictures at Bridge of Sighs, and then head outdoors with Balneario La Punta. Get ready for a full day of sightseeing on the next day: contemplate in the serene atmosphere at Church and Sanctuary of Saint Rose of Lima, take in the architecture and atmosphere at Iglesia y Convento de San Francisco, and then identify plant and animal life at Nor Yauyos-Cochas Landscape Reserve.

To find where to stay, maps, ratings, and other tourist information, read Lima tour itinerary builder website .

Traveling by flight from Bogota to Lima takes 5 hours. Alternatively, you can drive; or take a bus. In April, Lima is somewhat warmer than Bogota - with highs of 28°C and lows of 22°C. Wrap up your sightseeing on the 23rd (Mon) early enough to travel to La Paz.

Things to do in Lima

Outdoors Wildlife Parks

Side Trip

Balneario La Punta
Find places to stay Apr 21 — 23:
Highlights from your plan
Balneario La Punta ©
Balneario La Punta
Iglesia y Convento de San Francisco ©
Barranco ©
Barranco

2
nights
La Paz, Bolivia

La Paz ©
Take a moment to catch your breath as you commence your holiday in La Paz.
On the 24th (Tue), explore the striking landscape at Valley of the Moon, then make a trip to Plaza del Monticulo, then contemplate in the serene atmosphere at Iglesia de San Francisco, and finally pause for some serene contemplation at Catedral Basilica Menor de Nuestra Senora de la Paz. On the 25th (Wed), you'll have a packed day of sightseeing: look for gifts at Mistura - Manifestacion Creativa and then make a trip to San Miguel.

Plan a trip to La Paz easily and quickly by telling Inspirock to suggest an itinerary.

You can fly from Lima to La Paz in 6 hours. Alternatively, you can drive; or take a bus. The time zone difference moving from Peru Time (PET) to Bolivia Time (BOT) is 1 hour. Traveling from Lima in April, expect nights in La Paz to be much colder, around 1°C, while days are little chillier, around 17°C. Finish up your sightseeing early on the 25th (Wed) so you can travel to Natal.

Things to do in La Paz

Shopping Neighborhoods Nature
Find places to stay Apr 23 — 25:
Highlights from your plan
San Miguel ©
San Miguel
Valley of the Moon ©
Valley of the Moon
Iglesia de San Francisco ©
Iglesia de San Francisco

5
nights
Natal, Brazil

Natal ©
The promise of sun, sand, and surf generates plenty of tourism in Natal.
Relax by the water at Cacimbinhas Beach and Praias do Amor e do Moleque. Your cultural itinerary includes sights like Clidenor de Lima Galvao Museum and Metropolitan Cathedral. Venture out of the city with trips to Pirangi Cashew Tree (in Pirangi do Norte), Baia Formosa Beach (in Baia Formosa) and Cowboy's Museum (in Sao Jose de Mipibu). Next up on the itinerary: enjoy the sand and surf at Jacuma Beach, tour the pleasant surroundings at Buzios beach, hunt for treasures at Centro de Artesanato de Ponta Negra, and stop by Hand Craft Potiguar Mall.

For where to stay, more things to do, maps, and tourist information, go to the Natal day trip planner .

Traveling by flight from La Paz to Natal takes 13 hours. Alternatively, you can drive; or take a bus. The time zone changes from Bolivia Time (BOT) to Brasilia Time (BRT), which is usually a 1 hour difference. Traveling from La Paz in April, expect Natal to be warmer, temps between 36°C and 28°C. Wrap up your sightseeing on the 1st (Tue) early enough to travel to Florianopolis.

Things to do in Natal

Parks Outdoors Beaches

Side Trips

Cajueiro de Pirangi, Praias Do Amor E Do Moleque, Baia Formosa Beach, Cowboy's Museum, Clidenor de Lima Galvao Museum
Find places to stay Apr 25 — May 1:
Highlights from your plan
Cajueiro de Pirangi ©
Cajueiro de Pirangi
Praias Do Amor E Do Moleque ©
Praias Do Amor E Do Moleque
Cacimbinhas Beach ©
Cacimbinhas Beach

7
nights
Florianopolis, Brazil

Florianopolis ©
Divided between island and mainland, the distinctive city of Florianopolis charms visitors on first arrival with its impressive skyline.
Escape the urban bustle at Lagoinha do Leste and Lagoinha Beach (Trapiche). Relax by the water at Barra da Lagoa Beach and Forte Beach. Change things up with these side-trips from Florianopolis: Itapema (Itapema Beach & Meia-Praia Beach) and Morro do Macaco (in Bombinhas). There's lots more to do: tour the pleasant surroundings at Praia Brava, enjoy the sand and surf at Prainha da Barra da Lagoa, admire the sheer force of Praia da Solidao, and enjoy breathtaking views from Miorro da Lagoa.

Use Inspirock's suggestions to plan your Florianopolis trip and find the best activities and attractions for your vacation.

You can fly from Natal to Florianopolis in 8.5 hours. Alternatively, you can do a combination of flight, taxi, and bus; or drive. Traveling from Natal in May, things will get a bit cooler in Florianopolis: highs are around 26°C and lows about 19°C. Finish your sightseeing early on the 8th (Tue) so you can travel to Rio de Janeiro.

Things to do in Florianopolis

Parks Outdoors Beaches

Side Trips

Bombinhas, Itapema
Find places to stay May 1 — 8:
Highlights from your plan
Lagoinha do Leste ©
Lagoinha do Leste
Barra da Lagoa Beach ©
Barra da Lagoa Beach
Forte Beach ©
Forte Beach

3
nights
Rio de Janeiro, Brazil

Rio de Janeiro
Bustling with samba music and all-night street parties, no city encapsulates the spirit of Brazil better than Rio de Janeiro.
Start off your visit on the 9th (Wed): look for all kinds of wild species at Bosque da Barra, appreciate the history behind Corcovado Christ the Redeemer, and then take in panoramic vistas at Mirante Dona Marta. On the 10th (Thu), you'll have a packed day of sightseeing: tour the pleasant surroundings at Praia de Ipanema, enjoy the sand and surf at Pedra do Arpoador, then tour the pleasant surroundings at Copacabana Beach, and finally appreciate the extensive heritage of Avenida Atlantica.

To find more things to do, maps, ratings, and tourist information, read Rio de Janeiro trip builder site .

Traveling by flight from Florianopolis to Rio de Janeiro takes 2.5 hours. Alternatively, you can drive; or take a bus. In May, Rio de Janeiro is somewhat warmer than Florianopolis - with highs of 31°C and lows of 24°C. On the 11th (Fri), wrap the sightseeing up by early afternoon so you can travel back home.

Things to do in Rio de Janeiro

Parks Outdoors Beaches
Find places to stay May 8 — 11:
Highlights from your plan
Praia de Ipanema
Praia de Ipanema
Copacabana Beach ©
Copacabana Beach
Corcovado Christ the Redeemer ©
Corcovado Christ the Redeemer

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