16 days in Northwest Italy Itinerary

Virtually unchanged for the last six centuries, Venice is actually a group of islands made famous by a series of canals, bridges, monuments, piazzas, and narrow pedestrian lanes.

Eschew the tourist crowds and head to Basilica of St. Anthony and San Giorgio Maggiore. Doge's Palace and Peggy Guggenheim Collection will appeal to museum buffs. You'll find plenty of places to visit near Venice: Padua (Scrovegni Chapel & Chiesa degli Eremitani). There's still lots to do: contemplate in the serene atmosphere at Basilica di Santa Maria Gloriosa dei Frari, visit Cannaregio, take in the views from Ponte di Rialto, and pause for some serene contemplation at Scuola Grande di San Rocco.

For reviews, ratings, traveler tips, and more tourist information, read our Venice route builder website.

San Juan, Puerto Rico to Venice is an approximately 15-hour flight. The time zone difference moving from Atlantic Standard Time to Central European Standard Time is 5 hours. Traveling from San Juan in April, expect Venice to be colder, temps between 21°C and 11°C. Finish up your sightseeing early on the 4th (Sat) so you can go by car to Ravenna.

Famous for its wealth of original mosaics, Ravenna is a hub of artistic and cultural heritage.

Kick off your visit on the 5th (Sun): examine the collection at Archiepiscopal Museum, contemplate in the serene atmosphere at Battistero Neoniano (Battistero degli Ortodossi), contemplate in the serene atmosphere at Basilica di Sant'Apollinare Nuovo, take in the spiritual surroundings of Basilica di Sant'Apollinare in Classe, then take in the spiritual surroundings of Battistero degli Ariani, and finally take in the spiritual surroundings of Basilica San Vitale.

To find where to stay, more things to do, ratings, and tourist information, read Ravenna travel route builder website.

Getting from Venice to Ravenna by car takes about 2.5 hours. Other options: take a bus; or take a train. In April, plan for daily highs up to 21°C, and evening lows to 9°C. Finish up your sightseeing early on the 5th (Sun) so you can go by car to Assisi.

Rich in culture and religious tradition, Assisi is known as the birthplace of St.

You'll explore and learn at Museo della Porziuncola and B.A.T. Assisi. Explore hidden gems such as Duomo di Orvieto and Pozzo di San Patrizio. Change things up with these side-trips from Assisi: Cattedrale di Santa Maria Assunta Spoleto (in Spoleto), Cascata delle Marmore (in Marmore) and Civita di Bagnoregio (in Bagnoregio). The adventure continues: pause for some serene contemplation at Basilica di Santa Chiara, explore the historical opulence of Rocca Paolina, contemplate in the serene atmosphere at Cripta di San Francesco, and contemplate the long history of San Damiano.

To see traveler tips, reviews, more things to do, and tourist information, you can read our Assisi trip site.

Traveling by car from Ravenna to Assisi takes 3 hours. Alternatively, you can take a train; or take a bus. In April in Assisi, expect temperatures between 22°C during the day and 8°C at night. Finish up your sightseeing early on the 8th (Wed) so you can go by car to Rome.

Aptly nicknamed the Eternal City, Rome is the birthplace of the Roman Empire, one of the world's greatest civilizations ever.

Popular historic sites such as Colosseum and Vatican Museums are in your itinerary. You'll discover tucked-away gems like Arcibasilica di San Giovanni in Laterano and Church of St. Louis of the French. Step out of Rome to go to Ostia Antica and see Parco Archeologico di Ostia Antica, which is approximately 42 minutes away. The adventure continues: delve into the distant past at Pantheon, explore the world behind art at Centrale Montemartini, contemplate the long history of St. Peter's Basilica, and make a trip to Piazza Navona.

For ratings, photos, reviews, and more tourist information, read our Rome trip planning app.

You can drive from Assisi to Rome in 2.5 hours. Other options are to take a train; or take a bus. April in Rome sees daily highs of 24°C and lows of 11°C at night. Finish your sightseeing early on the 11th (Sat) so you can take a train to Florence.

Considered a cultural, artistic, and architectural jewel of Italy, Florence is the birthplace of the Italian Renaissance.

Popular historic sites such as Cathedral of Santa Maria del Fiore and Basilica San Miniato al Monte are in your itinerary. Do some cultural sightseeing at Florence Academy of Fine Arts and Duomo di Pisa. Venture out of the city with trips to Siena (Siena Tartufi (truffle hunting), Tabernacoli della Contrada della Civetta, &more), Camposanto (in Pisa) and Abbazia di San Galgano (in Chiusdino). There's still lots to do: admire the masterpieces at Pitti Palace, pause for some serene contemplation at Basilica - Santuario di Santo Stefano, admire the striking features of Loggia dei Lanzi, and get to know the fascinating history of Piazza del Duomo.

To find photos and more tourist information, refer to the Florence itinerary maker site.

You can take a train from Rome to Florence in 2.5 hours. Other options are to drive; or fly. In April, daily temperatures in Florence can reach 22°C, while at night they dip to 11°C. Wrap up your sightseeing by early afternoon on the 16th (Thu) to allow time for travel back home.