49 days in South America Itinerary

49 days in South America Itinerary

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49 days in South America Itinerary

Lima, Peru
Lima, Peru
— 5 nights
Fly:  1​h 45​min
Huaraz, Peru
— 2 nights
Drive:  5​h
Trujillo, Peru
— 2 nights
Fly + shuttle:  7​h 45​min
Mancora, Peru
— 2 nights
Drive:  7​h 45​min
Cuenca, Ecuador
— 2 nights
Drive:  3​h 30​min
Guayaquil, Ecuador
— 2 nights
Drive:  2​h 15​min
Montanita, Ecuador
— 1 night
Drive:  1​h 15​min
Salinas, Ecuador
— 2 nights
Drive:  1​h 45​min
Guayaquil, Ecuador
— 2 nights
Fly:  2​h
Baltra, Ecuador
— 2 nights
Fly + bus:  4​h 30​min
Quito, Ecuador
— 2 nights
bus + Fly:  3​h 30​min
Bogota, Colombia
— 2 nights
Fly:  1​h 30​min
Medellin, Colombia
— 2 nights
taxi + Fly:  2​h
Cartagena, Colombia
— 3 nights
Fly:  13​h 45​min
Iquitos, Peru
— 2 nights
Fly:  4​h 15​min
Huaraz, Peru
— 2 nights
Fly:  1​h 45​min
Lima, Peru
— 3 nights
Fly:  3​h
Cusco, Peru
— 2 nights
train:  3​h 15​min
Aguas Calientes, Peru
— 3 nights
train + taxi + Fly:  5​h 30​min
Arequipa, Peru
— 2 nights
Drive:  4​h 15​min
Puno, Peru
— 2 nights
Drive:  4​h
La Paz, Bolivia
— 2 nights
+4
bus + foot + shuttle + Fly + Drive:  5​h 45​min
Lima, Peru

6
days
Lima, Peru

Founded in 1535 by Spanish explorer Francisco Pizarro, Lima represents an interesting blend of modern attractions and preserved colonial architecture, much of it clustered in the World Heritage-listed city center.
Lima is known for historic sites, museums, shopping, nightlife, and parks. Your plan includes some of its best attractions: pause for some serene contemplation at Iglesia y Convento de San Francisco, get engrossed in the history at Larco Museum, shop like a local with Shopping Center Larcomar (Centro Comercial Larcomar), and stop by Dedalo Market.

To see ratings, photos, maps, and tourist information, use the Lima trip generator.

If you are flying in from United States, the closest major airport is Jorge Chávez International Airport. October in Lima sees daily highs of 69°F and lows of 61°F at night. Wrap up your sightseeing on the 13th (Fri) to allow time to travel to Huaraz.

Things to do in Lima

Historic Sites Parks Shopping
Accommodations
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Huaca Pucllana
Parque de la Reserva

2
days
Huaraz, Peru

One of the main cities in the Peruvian Andes, Huaraz mainly draws those seeking adventure out in the landscape.
Kick off your visit on the 14th (Sat): explore the ancient world of Monumento Nacional Wilcahuain Ruin, then witness a stunning natural landmark at Banos Termales de Monterrey, and then contemplate in the serene atmosphere at Iglesia La Soledad. On the 15th (Sun), you'll have a packed day of sightseeing: get outside with Infinite Adventures, then make a trip to Jiron Jose Olaya, and then stroll the grounds of Cementerio General Presbitero Villon.

To find ratings, photos, maps, and more tourist information, go to the Huaraz tour planner.

Traveling by flight from Lima to Huaraz takes 2 hours. Alternatively, you can take a bus; or drive. Wrap up your sightseeing on the 15th (Sun) early enough to drive to Trujillo.

Things to do in Huaraz

Historic Sites Outdoors Nature
Accommodations
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Iglesia La Soledad
Infinite Adventures
Jiron Jose Olaya

2
days
Trujillo, Peru

Considered the country's capital of culture, Trujillo was the birthplace of the North Group, a community of artists and intellectuals that included celebrated poet Cesar Vallejo and notable novelist Ciro Alegria.
On the 16th (Mon), delve into the distant past at Chan Chan, steep yourself in history at Casa Orbegoso, don't miss a visit to Plaza de Armas de Trujillo, then delve into the distant past at La Huaca del Sol, and finally contemplate the long history of Huaca del Sol y la Luna. Get ready for a full day of sightseeing on the next day: examine the collection at Museo Catedralicio, then take a stroll around Plazuela El Recreo, and then pause for some serene contemplation at Catedral de Trujillo - Catedral de Santa Maria.

To find where to stay, photos, more things to do, and more tourist information, go to the Trujillo trip planner.

Getting from Huaraz to Trujillo by car takes about 5 hours. Other options: take a bus. In October in Trujillo, expect temperatures between 68°F during the day and 61°F at night. Finish up your sightseeing early on the 17th (Tue) so you can travel to Mancora.

Things to do in Trujillo

Historic Sites Shopping Museums
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Chan Chan
Huaca del Sol y la Luna
La Huaca del Sol

2
days
Mancora, Peru

In a busy little beach town, Mancora tourism industry continues to grow, largely thanks to the sunniest climate of any region in the country.
Kick off your visit on the 18th (Wed): tour the pleasant surroundings at Las Pocitas Beach, relax and rejuvenate at some of the top local wellness centers, and then stop by PERRO COMEO. Keep things going the next day: look for all kinds of wild species at Wildlife Areas.

To find where to stay, maps, photos, and other tourist information, go to the Mancora online itinerary creator.

Traveling by combination of flight and shuttle from Trujillo to Mancora takes 8 hours. Alternatively, you can take a bus; or drive. Expect somewhat warmer temperatures when traveling from Trujillo in October; daily highs in Mancora reach 78°F and lows reach 67°F. On the 19th (Thu), wrap the sightseeing up by early afternoon so you can travel to Cuenca.

Things to do in Mancora

Outdoors Tours Wildlife
Accommodations
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2
days
Cuenca, Ecuador

Packed with impressive colonial architecture and a historic town center, Cuenca stands as perhaps the most charming city in the nation.
Kick off your visit on the 20th (Fri): explore the striking landscape of El Cajas National Park. Here are some ideas for day two: don't miss a visit to Plaza Abdon Calderon, then take in the exciting artwork at Homero Ortega, then explore the activities along Rio Tomebamba, and finally pause for some serene contemplation at Mirador de Turi.

For traveler tips, photos, ratings, and more tourist information, go to the Cuenca holiday planner.

Getting from Mancora to Cuenca by car takes about 6 hours. Traveling from Mancora in October, things will get little chillier in Cuenca: highs are around 72°F and lows about 53°F. Finish up your sightseeing early on the 21st (Sat) so you can go by car to Guayaquil.

Things to do in Cuenca

Nature Parks Historic Sites
Accommodations
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El Cajas National Park
Mirador de Turi
Homero Ortega

2
days
Guayaquil, Ecuador

Hills dotted with colorful houses and waterfront promenades typify Guayaquil, Ecuador's largest city and commercial center.
Start off your visit on the 22nd (Sun): don't miss a visit to Parque Historico Guayaquil, then explore the world behind art at Museum of Anthropology and Contemporary Art, and then meet the residents at Parque de las Iguanas. Get ready for a full day of sightseeing on the next day: wander the streets of Cerro Santa Ana, then take a stroll through Las Penas, then take a leisurely stroll along Malecon 2000, and finally take in the architecture and atmosphere at Catedral Metropolitana de Guayaquil.

For photos, reviews, more things to do, and other tourist information, go to the Guayaquil trip itinerary builder.

Traveling by car from Cuenca to Guayaquil takes 3.5 hours. Alternatively, you can take a bus. Prepare for somewhat warmer weather when traveling from Cuenca in October: high temperatures in Guayaquil hover around 86°F and lows are around 70°F. Cap off your sightseeing on the 23rd (Mon) early enough to go by car to Montanita.

Things to do in Guayaquil

Neighborhoods Zoos & Aquariums Outdoors
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Las Penas
Cerro Santa Ana
Parque Historico Guayaquil

1
day
Montanita, Ecuador

A small, secluded coastal town with a laid-back atmosphere and a countercultural hippy vibe, Montanita has a reputation as a seaside getaway with a twist.
Start off your visit on the 24th (Tue): admire all the interesting features of Montanita Spanish School - Day Classes and then stroll through Playa Montanita.

For other places to visit, traveler tips, reviews, and other tourist information, read Montanita itinerary builder.

Traveling by car from Guayaquil to Montanita takes 2.5 hours. Alternatively, you can take a bus. In October, daily temperatures in Montanita can reach 82°F, while at night they dip to 70°F. Cap off your sightseeing on the 24th (Tue) early enough to go by car to Salinas.

Things to do in Montanita

Beaches Outdoors Parks

Side Trip

Playa Montanita
Accommodations
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Playa Montanita

2
days
Salinas, Ecuador

The coastal city of Salinas is the westernmost city on mainland Ecuador and a leading tourist destination.
Kick off your visit on the 25th (Wed): stroll through Playa de Chipipe and then enjoy the sand and surf at Playa Las Salinas. Get ready for a full day of sightseeing on the 26th (Thu): take in the waterfront at Malecon Salinas, then identify plant and animal life at La Loberia, and then get outside with La Chocolatera.

To see photos, maps, more things to do, and tourist information, use the Salinas vacation builder.

You can drive from Montanita to Salinas in 1.5 hours. Another option is to take a bus. Traveling from Montanita in October, expect nights in Salinas to be about the same, around 70°F, while days are little chillier, around 77°F. Finish up your sightseeing early on the 26th (Thu) so you can go by car to Guayaquil.

Things to do in Salinas

Outdoors Parks Beaches
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Playa de Chipipe
La Loberia
Playa Las Salinas

2
days
Guayaquil, Ecuador

Start off your visit on the 27th (Fri): head off the coast to Isla Santay, then admire the landmark architecture of Torre Morisca, and then head outdoors with Malecon del Salado. On your second day here, take in the spiritual surroundings of Iglesia San Francisco, examine the collection at Presley Norton Museum, then don't miss a visit to Captain Morgan's Pirate Ship, then don't miss a visit to Hemiciclo de la Rotonda, and finally stop by Plaza Lagos.

To see other places to visit, ratings, more things to do, and other tourist information, use the Guayaquil custom trip planner.

Getting from Salinas to Guayaquil by car takes about 2 hours. Other options: take a bus. When traveling from Salinas in October, plan for somewhat warmer days in Guayaquil, with highs around 86°F, while nights are about the same with lows around 70°F. Finish your sightseeing early on the 28th (Sat) so you can travel to Baltra.

Things to do in Guayaquil

Outdoors Nature Parks
Accommodations
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Malecon del Salado
Plaza Lagos
Isla Santay

2
days
Baltra, Ecuador

Kick off your visit on the 29th (Sun): head outdoors with Tip Top IV, make a trip to Ecua-Andino Galapagos, and then step off the mainland to explore North Seymour Island.

For reviews, where to stay, and other tourist information, read Baltra itinerary planner.

You can fly from Guayaquil to Baltra in 2 hours. When traveling from Guayaquil in October, plan for slightly colder days in Baltra, with highs around 80°F, while nights are about the same with lows around 71°F. On the 30th (Mon), you'll travel to Quito.

Things to do in Baltra

Outdoors Nature Parks
Accommodations
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North Seymour Island

2
days
Quito, Ecuador

High in the Andean foothills, Quito remains one of the world's most photogenic capital cities, featuring two dramatic mountain ranges as its backdrop.
Start off your visit on the 31st (Tue): contemplate in the serene atmosphere at Basilica del Voto Nacional, appreciate the extensive heritage of Quito Old Town, then take in the spiritual surroundings of San Francisco Church (Iglesia de San Francisco), then admire the striking features of Iglesia de La Compania de Jesus, and finally admire the landmark architecture of Palacio de Gobierno. On your second day here, don't miss a visit to Plaza de la Independencia (Plaza Grande), admire all the interesting features of La Ronda, then take an in-depth tour of Museo Templo del Sol Pintor Ortega Maila, and finally get curious at Mitad del Mundo.

To find ratings, maps, other places to visit, and other tourist information, go to the Quito trip builder.

You can do a combination of flight and bus from Baltra to Quito in 4.5 hours. Expect little chillier temperatures when traveling from Baltra in October; daily highs in Quito reach 70°F and lows reach 52°F. Finish your sightseeing early on the 1st (Wed) to allow enough time to travel to Bogota.

Things to do in Quito

Historic Sites Museums Childrens Museums
Accommodations
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2
days
Bogota, Colombia

Colombia's heart and soul, Bogota has earned the nickname "Athens of South America" thanks to its abundance of universities, libraries, and lower-level schools.
On the 2nd (Thu), browse the collection at Biblioteca Virgilio, contemplate in the serene atmosphere at Mount Monserrate, and then examine the collection at Gold Museum (Museo del Oro). Keep things going the next day: admire the striking features of Torre Colpatria, explore the world behind art at Museo Botero del Banco de la Republica, and then look for all kinds of wild species at Jardin Botanico de Bogota Jose Celestino Mutis.

To find other places to visit, maps, more things to do, and more tourist information, read our Bogota vacation planner.

Traveling by combination of bus and flight from Quito to Bogota takes 3.5 hours. Alternatively, you can take a bus; or drive. November in Bogota sees daily highs of 67°F and lows of 48°F at night. Cap off your sightseeing on the 3rd (Fri) early enough to travel to Medellin.

Things to do in Bogota

Parks Museums Wildlife
Accommodations
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Mount Monserrate
Gold Museum (Museo del Oro)

2
days
Medellin, Colombia

Nestled between rising hills in a narrow valley, Medellin serves as an energetic melting pot of people from all socio-economic classes.
Start off your visit on the 4th (Sat): make a trip to Plaza Botero, meet the residents at Parque Explora, and then take in nature's colorful creations at Jardin Botanico de Medellin. On the next day, steep yourself in history at Pueblito Paisa and then take in the local highlights with Walking tours.

To see reviews, traveler tips, more things to do, and more tourist information, you can read our Medellin online itinerary creator.

Traveling by flight from Bogota to Medellin takes 1.5 hours. Alternatively, you can drive; or do a combination of bus and taxi. Expect a bit warmer temperatures when traveling from Bogota in November; daily highs in Medellin reach 80°F and lows reach 63°F. Wrap up your sightseeing on the 5th (Sun) to allow time to travel to Cartagena.

Things to do in Medellin

Tours Parks Zoos & Aquariums
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Walking tours
Parque Explora
Plaza Botero

2
days
Cartagena, Colombia

The site of the continent's first Spanish colony, Cartagena retains much of its colonial flavor thanks to a World Heritage-listed old town, encircled by old walls and protected by imposing fortresses.
Start off your visit on the 6th (Mon): contemplate the long history of Walled City of Cartagena, then gain insight at Plaza Santo Domingo, and then make a trip to Plaza de San Diego. On the 7th (Tue), you'll have a packed day of sightseeing: take an in-depth tour of Museo del Oro Zenu, don't miss a visit to Plaza Bolivar, admire the striking features of Las Bovedas, explore the historical opulence of San Felipe de Barajas Castle, then take in the spiritual surroundings of Convento La Popa de la Galera, and finally make a trip to La Popa Monastery.

To find photos, where to stay, maps, and more tourist information, refer to the Cartagena travel itinerary planner.

Traveling by combination of taxi and flight from Medellin to Cartagena takes 2 hours. Alternatively, you can drive; or take a bus. In November, Cartagena is somewhat warmer than Medellin - with highs of 89°F and lows of 78°F. Wrap up your sightseeing by early afternoon on the 8th (Wed) to allow time for travel to Iquitos.

Things to do in Cartagena

Historic Sites Museums
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San Felipe de Barajas Castle
Walled City of Cartagena
Convento La Popa de la Galera

2
days
Iquitos, Peru

The largest city in the Peruvian Amazon and the world's largest metropolis unreachable by road, Iquitos represents a major starting point for river and rainforest adventures.
On the 9th (Thu), take a stroll through Belen, then look for all kinds of wild species at Amazon Rescue Center, and then admire nature's wide array of creatures at Quistacocha Zoo. Get ready for a full day of sightseeing on the 10th (Fri): identify plant and animal life at Pilpintuwasi Butterfly Farm, then admire the striking features of Casa de Fierro, then don't miss a visit to Plaza de Armas de Iquitos, and finally identify plant and animal life at La Isla De Los Monos.

To find reviews, ratings, traveler tips, and tourist information, use the Iquitos trip itinerary builder.

Explore your travel options from Cartagena to Iquitos with the Route module. Traveling from Cartagena in November, you can expect nighttime temperatures to be little chillier in Iquitos, with lows of 73°F. Wrap up your sightseeing on the 10th (Fri) early enough to travel to Huaraz.

Things to do in Iquitos

Parks Wildlife Zoos & Aquariums
Accommodations
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Quistacocha Zoo
La Isla De Los Monos
Amazon Rescue Center

2
days
Huaraz, Peru

Kick off your visit on the 11th (Sat): explore the ancient world of Monumento Nacional Wilcahuain Ruin, then take in the natural beauty of Banos Termales de Monterrey, and then look for gifts at Mercado Central. On your second day here, identify plant and animal life at Callejon de Conchucos, then make a trip to Jiron Jose Olaya, and then take in the spiritual surroundings of Iglesia La Soledad.

For where to stay, ratings, photos, and other tourist information, go to the Huaraz vacation planner.

Traveling by flight from Iquitos to Huaraz takes 4.5 hours. Alternatively, you can do a combination of flight and car. Finish your sightseeing early on the 12th (Sun) so you can travel to Lima.

Things to do in Huaraz

Parks Wildlife Nature
Accommodations
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Iglesia La Soledad
Mercado Central
Jiron Jose Olaya

2
days
Lima, Peru

Kick off your visit on the 13th (Mon): get the lay of the land with Walking tours, look for gifts at C C Inka Plaza, and then take in the spiritual surroundings of Monastery of Santo Domingo (Iglesia y Monasterio de Santo Domingo). Get ready for a full day of sightseeing on the next day: delve into the distant past at Pachacamac and then examine the collection at National Museum of Archaeology, Anthropology and History.

To find other places to visit, where to stay, photos, and tourist information, refer to the Lima trip itinerary builder.

Getting from Huaraz to Lima by flight takes about 2 hours. Other options: take a bus; or drive. Wrap up your sightseeing on the 15th (Wed) to allow time to travel to Cusco.

Things to do in Lima

Historic Sites Tours Museums
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2
days
Cusco, Peru

Capital of the Inca Empire for three centuries, World Heritage-listed Cusco is now a major tourist destination, drawing nearly 2 million annual tourists with its well-preserved colonial architecture and proximity to Machu Picchu.
Start off your visit on the 15th (Wed): explore the ancient world of Centro Historico De Cusco, explore the ancient world of Sacred Valley of the Incas, then stop by Hilo, and finally take in the spiritual surroundings of Catedral del Cuzco o Catedral Basilica de la Virgen de la Asuncion. On the 16th (Thu), you'll have a packed day of sightseeing: explore the ancient world of Sacsayhuaman, steep yourself in history at Plaza de Armas, and then explore the ancient world of Winawayna.

To see more things to do, other places to visit, traveler tips, and other tourist information, use the Cusco travel itinerary planner.

You can fly from Lima to Cusco in 3 hours. Other options are to take a bus; or drive. Plan for slightly colder nights when traveling from Lima in November since evenings lows in Cusco dip to 45°F. Finish your sightseeing early on the 17th (Fri) to allow enough time to travel to Aguas Calientes.

Things to do in Cusco

Historic Sites Shopping

Side Trips

Winawayna, Sacred Valley of the Incas
Accommodations
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Sacsayhuaman
Plaza de Armas
Centro Historico De Cusco

2
days
Aguas Calientes, Peru

Serving as the gateway to the ruins of Machu Picchu, Aguas Calientes is little more than a glorified cloud-forest village, housing just over a thousand permanent residents and featuring all of two streets.
Start off your visit on the 17th (Fri): explore the ancient world of Intipuncu and then don't miss a visit to Machu Picchu. On the 18th (Sat), you'll have a packed day of sightseeing: admire the natural beauty at Los Jardines de Mandor, take in the natural beauty of Hot Springs (Aguas Calientes), and then soothe aching muscles at some of the top local wellness centers.

For maps, other places to visit, ratings, and other tourist information, refer to the Aguas Calientes trip generator.

You can take a train from Cusco to Aguas Calientes in 3.5 hours. Alternatively, you can drive. Finish your sightseeing early on the 19th (Sun) to allow enough time to travel to Arequipa.

Things to do in Aguas Calientes

Historic Sites Parks Nature

Side Trip

Machu Picchu
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Machu Picchu
Intipuncu
Los Jardines de Mandor

2
days
Arequipa, Peru

In an area dominated three imposing volcanoes, Arequipa vacations allow visitors to admire well-preserved colonial architecture in a dramatic setting.
Start off your visit on the 19th (Sun): explore the stunning scenery at Colca Canyon, then examine the collection at Santa Catalina Monastery, and then admire the landmark architecture of Plaza de Armas. Keep things going the next day: take in the architecture and atmosphere at Cathedral of Arequipa Museum, contemplate the long history of Historic Centre of Arequipa, admire the striking features of Casa del Moral, then take in panoramic vistas at Yanahuara, and finally get engrossed in the history at Museo Santuarios Andinos.

To find ratings, reviews, maps, and more tourist information, refer to the Arequipa tour planner.

Traveling by combination of train and flight from Aguas Calientes to Arequipa takes 5.5 hours. Alternatively, you can drive; or do a combination of train and bus. Expect a daytime high around 70°F in November, and nighttime lows around 49°F. Finish up your sightseeing early on the 21st (Tue) so you can go by car to Puno.

Things to do in Arequipa

Museums Historic Sites Nature
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Santa Catalina Monastery
Casa del Moral
Plaza de Armas

2
days
Puno, Peru

Hugging the western tip of Lake Titicaca, Puno serves as a melting pot of indigenous and imported cultures, and makes a great base for explorations around the region.
Kick off your visit on the 21st (Tue): explore the ancient world of Sillustani and then step off the mainland to explore Taquile Island. Here are some ideas for day two: stroll through Parque Pino, head off the coast to Uros Floating Islands, and then explore the activities along Lake Titicaca.

For maps, reviews, photos, and more tourist information, go to the Puno trip itinerary maker.

You can drive from Arequipa to Puno in 4.5 hours. Alternatively, you can take a bus. Expect little chillier evenings in Puno when traveling from Arequipa in November, with lows around 37°F. Cap off your sightseeing on the 23rd (Thu) early enough to go by car to La Paz.

Things to do in Puno

Parks Nature Historic Sites
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Taquile Island
Uros Floating Islands
Lake Titicaca

2
days
La Paz, Bolivia

Take a moment to catch your breath as you commence your holiday in La Paz.
Kick off your visit on the 23rd (Thu): take in the dramatic natural features at Valley of the Moon and then steep yourself in history at Tiwanaku. Here are some ideas for day two: grab your bike and head to Yungas Road.

To find where to stay, reviews, maps, and other tourist information, refer to the La Paz itinerary maker.

Traveling by car from Puno to La Paz takes 4 hours. Alternatively, you can take a bus. The time zone difference when traveling from Puno to La Paz is 1 hour. When traveling from Puno in November, plan for slightly colder days in La Paz, with highs around 62°F, while nights are about the same with lows around 37°F. You will have some time to spend on the 25th (Sat) before leaving for home.

Things to do in La Paz

Parks Outdoors Trails
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Valley of the Moon
Tiwanaku
Yungas Road

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